Tigecycline (open C-ring D-ring) Quinone Trifluoroacetic Acid Salt

CAS: 1268494-46-7 76-05-1

Ref. TR-T440035

Produktinformation

• Name: Tigecycline (open C-ring D-ring) Quinone Trifluoroacetic Acid Salt
• Synonyme: 4-[[(2S)-8-(Dimethylamino)-6-[[2-[(1,1-dimethylethyl)amino]acetyl]amino]-1,2,3,4-tetrahydro-5-hydroxy-4-oxo-2-naphthalenyl]methyl]-2,5-dihydroxy-3,6-dioxo-1,4-cyclohexadiene-1-carboxamide Trifluoroacetic Acid Salt

Beschreibung

Applications Tigecycline (open C-ring D-ring) quinone Trifluoroacetic Acid Salt is a salt of Tigecycline (open C-ring D-ring) quinone, an impurity of Tigecycline (T440015). Tigecycline (open C-ring D-ring) quinone is one of the very few glycylcycline antimicrobials that exhibit activity against Gram-negative bacteria and also one of the few that also circumvent around the major resistance mechanisms of tetracycline.
References Grosse, E., et al.: Clin. Infect. Dis. (Supplement 5), 41, S341 (2005); Livermore, D.: J. Antimicrob. Chemoth., 56, 611 (2005); Stein, G. & Craig, W.: Clin. Infect. Dis., 43, 518 (2006)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 528.55 + x(114.02)
• Formel: C₂₆H₃₂N₄O₈•xC₂HF₃O₂)
• Farbe/Form: Neat
• InChl: InChI=1S/C26H32N4O8.C2HF3O2/c1-26(2,3)28-10-17(32)29-14-9-15(30(4)5)12-6-11(8-16(31)18(12)22(14)35)7-13-20(33)23(36)19(25(27)38)24(37)21(13)34;3-2(4,5)1(6)7/h9,11,28,33,35,37H,6-8,10H2,1-5H3,(H2,27,38)(H,29,32);(H,6,7)/t11-;/m0./s1