(R)-(+)-Timolol Maleate

CAS: 26839-77-0

Ref. TR-T443705

Produktinformation

• Name: (R)-(+)-Timolol Maleate
• Synonyme: Timolol Maleate Imp. A (EP), (2R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]-propan-2-ol (Z)-Butenedioate, (2R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol (2Z)-2-butenedioate, (R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol (Z)-2-Butenedioate (1:1) (salt), 1,2,5-Thiadiazole, 2-propanol deriv., (+)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole hydrogen maleate, (+)-Timolol maleate, (R)-Timolol hydrogen maleate, d-Timolol maleate, (+)-3-[3-(Tert-Butylamino)-2-Hydroxypropoxy]-4-Morpholino-1,2,5-Thiadiazole Maleate, (-)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-2-propanol maleate, (R)-(+)-Timolol maleate, 1,2,5-Thiadiazole, 2-propanol deriv., 1-(tert-Butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol (2Z)-but-2-enedioate (1:1), 1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol (2Z)-but-2-enedioate (salt), 2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-, (+)-, maleate (1:1) (salt), (-)-, 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2R)-, (2Z)-2-butenedioate (1:1), 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2R)-, (2Z)-2-butenedioate (1:1) (salt), 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (R)-, (Z)-2-butenedioate (1:1) (salt), 248-034-7, D-Timolol maleate

Beschreibung

Impurity Timolol EP A; Timolol BP Impurity A; Timolol USP Related Compound A
Applications Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent.Timolol EP A; Timolol BP Impurity A; Timolol USP Related Compound A
References Wasson, et al.: J. Med. Chem., 15, 651 (1972), Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972), Heel, R.C., et al.: Drugs, 17, 38 (1979), Rofman, B.A., et al.: Hypertension, 2, 643 (1980), Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641 (1987),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 432.49
• Formel: C₁₃H₂₄N₄O₃S·C₄H₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C13H24N4O3S.C4H4O4/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17;5-3(6)1-2-4(7)8/h10,14,18H,4-9H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t10-;/m1./s1
• InChI Key: InChIKey=WLRMANUAADYWEA-ASSQPYIHSA-N
• SMILES: CC(C)(C)NC[C@@H](O)COc1nsnc1N1CCOCC1.O=C(O)/C=C\C(=O)O