Tizoxanide

CAS: 173903-47-4

Ref. TR-T450100

Produktinformation

• Name: Tizoxanide
• Synonyme: 2-hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide, 2-Hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide, 2-Hydroxy-N-(5-nitro-2-thiazolyl)benzamide, Benzamide, 2-hydroxy-N-(5-nitro-2-thiazolyl)-, Nsc 697856, TIZ

Beschreibung

Applications A metabolite of Nitazoxanide (N490100); a potent inhibitor of hepatitis B virus and hepatitis C virus. Kills Mycobacterium tuberculosis.
References Allen, M., et al.: Hepatology, 27, 1670 (1998), Blight, K., et al.: Science, 290, 1972 (2000), Blight, K., et al.: J. Virol., 77, 3181 (2003), Courcambeck, J., et al.: Antivir Ther., 11, 847 (2006), Hoffman, P., et al.: Antimicrob. Agents Chemother., 51, 868 (2007); de Carvalho et. al., J. Med. Chem., 52, 5789 (2009)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 265.25
• Formel: C₁₀H₇N₃O₄S
• Farbe/Form: Off-White To Light Yellow
• InChl: InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
• SMILES: O=C(Nc1ncc([N+](=O)[O-])s1)c1ccccc1O