N-Boc Tobramycin

CAS: 66266-14-6

Ref. TR-T523995

Produktinformation

• Name: N-Boc Tobramycin
• Synonyme: O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-[2-amino-2,3,6-trideoxy-6-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-D-ribo-hexopyranosyl-(1-4)]-2-deoxy-D-streptamine
• Marke: TRC

Beschreibung

Applications N-Boc Tobramycin is an intermediate used in the synthesis of O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-D-streptamine (A604395), which is an impurity of Tobramycin (T524000), a single factor antibiotic comprising about 10% of nebramycin, the aminoglycosidic antibiotic complex produced by Streptomyces tenebrarius.
References Koch, K.F., et al.: Antimicrob. Agents Chemother., 309 (1970); Welles, J.S., et al.: Toxicol. Appl. Pharmacol., 22, 332 (1972); Dash, A.K., et al.: Anal. Profiles Drug Subs. Excip., 24, 579 (1996)

Chemische Eigenschaften

• Molekulargewicht: 567.63
• Formel: C₂₃H₄₅N₅O₁₁
• Farbe/Form: Neat
• InChl: InChI=1S/C23H45N5O11/c1-23(2,3)39-22(34)28-6-12-11(30)5-10(26)20(35-12)37-18-8(24)4-9(25)19(17(18)33)38-21-16(32)14(27)15(31)13(7-29)36-21/h8-21,29-33H,4-7,24-27H2,1-3H3,(H,28,34)/t8-,9+,10+,11-,12+,13+,14-,15+,16+,17-,18+,19-,20+,21+/m0/s1
• InChI Key: InChIKey=LEZCDKLNLRLXIJ-YJDUPYBASA-N
• SMILES: CC(C)(C)OC(=O)NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O