Tocofersolan

CAS: 9002-96-4

Ref. TR-T526075

Produktinformation

• Name: Tocofersolan
• Synonyme: D 1T, Vitamin E Polyethylene Glycol Succinate, Mono[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] Succinate Polyoxyethylene Ether, TPGS, Tocophersolan, Vitamin E-TPGS,[2R-[2R*(4R*,8R*)]]-α-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-hydroxypoly(oxy-1,2-ethanediyl), D-α-Tocopherol Polyethylene Glycol 1000 Succinate
• Marke: TRC
• Beschreibung: Applications Tocofersolan is a polyethylene glycol derivative of α-Tocopherol (T526125). Tocofersolan is a synthetic water-soluble vitamin E unlike its natural counterpart which are fat soluble. Tocofersolan is used in pediatrics in the treatment vitamin E-deficient cholestatic children. Tocofersolan has potential application as a absorption enhancer in drug delivery systems. Typical batch, n = 21References Socha, P. et al.: J. Pediatric Gastroenterol. Nutr., 24, 189 (1997); Chang, T. et al.: Clin. Pharmacol. Therap., 59, 297 (1996); Wu, S.H.W. et al.: Pharmac. Technol., 23, 52 (1999)

Chemische Eigenschaften

• Molekulargewicht: 530.78 + (44.05)n
• Formel: C₃₃H₅₄O₅(C₂H₄O)n
• Farbe/Form: Neat
• InChl: InChI=1S/C35H58O6/c1-24(2)12-9-13-25(3)14-10-15-26(4)16-11-20-35(8)21-19-30-29(7)33(27(5)28(6)34(30)41-35)40-32(38)18-17-31(37)39-23-22-36/h24-26,36H,9-23H2,1-8H3/t25-,26-,35-/m1/s1
• InChI Key: InChIKey=AOBORMOPSGHCAX-AZAGJHQNSA-N
• SMILES: Cc1c(C)c2c(c(C)c1OC(=O)CCC(=O)OCCO)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2