Tretazicar (>94%)

CAS: 21919-05-1

Ref. TR-T719800

Produktinformation

• Name: Tretazicar (>94%)
• Synonyme: 5-(1-Aziridinyl)-2,4-dinitrobenzamide, 2,4-Dinitro-5-ethyleneiminobenzamide, 2,4-Dinitroethyleneiminobenzamide, 5-(1-Aziridinyl)-2,4-dinitrobenzamide, 5-Aziridino-2,4-dinitrobenzamide, 5-Aziridinyl-2,4-dinitrobenzamide, CB 1954, NSC 115829, 5-(Aziridin-1-Yl)-2,4-Dinitrobenzamide, Benzamide, 5-(1-aziridinyl)-2,4-dinitro-, Cb-1954, Tretazicar

Beschreibung

Applications Tretazicar is an anticancer prodrug used in gene therapy research and is known to be activated by NAD(P)H Quinone Oxidoreductase 2.
References Pisharath, H., et al.: Comp. Med., 57, 241 (2007); Christofferson, A., et al.: Biochem. Soc. Trans., 37, 413 (2009); Prosser, G.A., et al.: Biochem. Pharmacol., 85, 1091 (2013); Bot, C., et al.: Antimicrob. Agents. Chemotherap., 54, 4246 (2010); Richard, J.K., et al.: Cancer. Res., 60, 4179 (2000);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 252.18
• Formel: C₉H₈N₄O₅
• Reinheit: >94%
• Farbe/Form: Neat
• SMILES: NC(=O)c1cc(N2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-]