N10-Trifluoroacetylpteroic Acid

CAS: 37793-53-6

Ref. TR-T789700

Produktinformation

• Name: N10-Trifluoroacetylpteroic Acid
• Synonyme: 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl](2,2,2-trifluoroacetyl)amino]benzoic Acid, 4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl](trifluoroacetyl)amino]benzoic Acid, N10-(Trifluoroacetyl)pteroic acid, 4-{[(2-Amino-4-Oxo-1,4-Dihydropteridin-6-Yl)Methyl](Trifluoroacetyl)Amino}Benzoic Acid, Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl](2,2,2-trifluoroacetyl)amino]-

Beschreibung

Stability Hygroscopic
Applications N10-Trifluoroacetylpteroic acid is a derivative of Pteroic acid (P840110), both of which are used as reagents to synthesize target ligands, like Folic acid (F680300), that have the ability to deliver chemotherapeutic agents specifically to cancer cells.
References Leamon, C., et al.: Bioconjugate Chem., 14, 738 (2003); Leamon, C., et al.: J. Drug Target., 7, 157 (1999); Yonghua, Z., et al.: Anal. Biochem., 332, 168 (2004)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 408.29
• Formel: C₁₆H₁₁F₃N₆O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C16H11F3N6O4/c17-16(18,19)14(29)25(9-3-1-7(2-4-9)13(27)28)6-8-5-21-11-10(22-8)12(26)24-15(20)23-11/h1-5H,6H2,(H,27,28)(H3,20,21,23,24,26)
• InChI Key: InChIKey=IJGIHDXKYQLIMA-UHFFFAOYSA-N
• SMILES: Nc1nc2[nH]cc(CN(C(=O)C(F)(F)F)c3ccc(C(=O)O)cc3)nc-2c(=O)n1