7-(Trifluoromethyl)-1H-indole-2,3-dione-d2

CAS: 391-12-8

Ref. TR-T791302

Produktinformation

• Name: 7-(Trifluoromethyl)-1H-indole-2,3-dione-d2
• Synonyme: 7-(Trifluoromethyl)isatin-d2, Buttpark 24\07-40, 7-(Trifluoromethyl)Indoline-2,3-Dione, 7-(Trifluoromethyl)Isatin, 7-(Trifluoromethyl)-1H-Indole-2,3-Dione, 7-(Trifluoromethyl)Indole-2,3-Dione
• CAS: 391-12-8

Beschreibung

Applications 7-(Trifluoromethyl)1H-indole-2,3-dione-d2 is a labelled 7-(Trifluoromethyl)1H-indole-2,3-dione (T791300), an inhibitor of COX-1, COX-2, and β-catenin. Useful in the treatment of diseases such as: lung cancer, diabetes and Alzheimer's disease.
References Medwid, J., et al.: J. Med. Chem., 33, 1230 (1990), Collins, L., et al.: Antimicrob. Agents Chemother., 41, 1004 (1997), Dandia, A., et al.: Bioorg. Med. Chem., 14, 2409 (2006)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 217.141
• Formel: C₉D₂H₂F₃NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C9H4F3NO2/c10-9(11,12)5-3-1-2-4-6(5)13-8(15)7(4)14/h1-3H,(H,13,14,15)/i1D,2D
• InChI Key: InChIKey=MXLDJTXXAYVWDF-QDNHWIQGSA-N
• SMILES: [2H]c1cc(C(F)(F)F)c2c(c1[2H])C(=O)C(=O)N2