2-[(3,3,3-Trifluoropropyl)thio]adenosine

CAS: 163706-51-2

Ref. TR-T792665

Produktinformation

• Name: 2-[(3,3,3-Trifluoropropyl)thio]adenosine
• Synonyme: (2R,3R,4S,5R)-2-[6-amino-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

Beschreibung

Applications 2-[(3,3,3-Trifluoropropyl)thio]adenosine is used as a reactant in the synthesis of Cangrelor (C175230). It was also used in the synthesis of a host of compounds that act as highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 ADP receptors.
References Ye, Tianjian, et al.: Zhejiang Yongning Pharmaceutical Co., CN 105949258 A 20160921 (2016); Yanachkov, Ivan B., et al.: Euro. J. of Med. Chem., 107, 204-218 (2016);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 395.358
• Formel: C₁₃H₁₆F₃N₅O₄S
• Farbe/Form: Neat
• InChl: InChI=1S/C13H16F3N5O4S/c14-13(15,16)1-2-26-12-19-9(17)6-10(20-12)21(4-18-6)11-8(24)7(23)5(3-22)25-11/h4-5,7-8,11,22-24H,1-3H2,(H2,17,19,20)/t5-,7-,8-,11-/m1/s1
• InChI Key: InChIKey=YXQSQDQDYVOJLV-IOSLPCCCSA-N
• SMILES: Nc1nc(SCCC(F)(F)F)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O