3,3’,5-Triiodo-L-thyronine Methyl Ester

CAS: 54914-53-3

Ref. TR-T795373

Produktinformation

• Name: 3,3’,5-Triiodo-L-thyronine Methyl Ester
• Synonyme: Liothyronine Methyl Ester, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-Tyrosine methyl ester, 3,5,3'-Triiodo-L-thyronine methyl ester, L-Triiodothyronine methyl ester
• CAS: 54914-53-3

Beschreibung

Applications 3,3’,5-Triiodo-L-thyronine Methyl Ester is an intermediate in synthesizing 3,3’,5-Triiodo-L-thyronine O-β-D-Glucuronide (T795405), a O-glucuronide derivative of 3,3’,5-Triiodo-L-thyronine (T795380); one of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
References Gross, J., et al.: Lancet I, 439 (1952); Roche, J., et al.: Biochim. Biophys. Acta, 11, 215 (1953); Chacon, M.A., et al.: J. Pediatr., 99, 758 (1981); Chopra, I.J., et al.: Thyroid, 6, 255 (1996)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 665.00
• Formel: C₁₆H₁₄I₃NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C16H14I3NO4/c1-23-16(22)13(20)6-8-4-11(18)15(12(19)5-8)24-9-2-3-14(21)10(17)7-9/h2-5,7,13,21H,6,20H2,1H3/t13-/m0/s1
• InChI Key: InChIKey=ZCDFHKCLWIMBKP-ZDUSSCGKSA-N
• SMILES: COC(=O)[C@@H](N)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1