O-di-TMS 2-Arachidonyl Glycerol-d5

CAS: 223259-26-5

Ref. TR-T876516

Produktinformation

• Name: O-di-TMS 2-Arachidonyl Glycerol-d5
• Synonyme: [1,1,2,3,3-pentadeuterio-1,3-bis[tri(propan-2-yl)silyloxy]propan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate

Beschreibung

Applications O-di-TMS 2-Arachidonyl Glycerol-d5 is an intermediate used in the synthesis of 2-Arachidonyl Glycerol-d5 (A765052), which is a labelled 2-Arachidonoylglycerol (A765050). It is a major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors. It plays an inhibitory role in the bombesin-induced activation of central adrenomedullary outflow in rats.
References Yokotani, K., et al.: Eur. J. Pharmacol., 512, 29 (2005), Jensen, R., et al.: Pharmacol. Rev., 60, 1 (2008), Lu, L., et al.: Eur. J. Pharmacol., 590, 177 (2008),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 696.257
• Formel: C₄₁D₅H₇₃O₄Si₂
• Farbe/Form: Neat
• InChl: InChI=1S/C41H78O4Si2/c1-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29-30-31-41(42)45-40(32-43-46(34(2)3,35(4)5)36(6)7)33-44-47(37(8)9,38(10)11)39(12)13/h18-19,21-22,24-25,27-28,34-40H,14-17,20,23,26,29-33H2,1-13H3/b19-18-,22-21-,25-24-,28-27-/i32D2,33D2,40D
• InChI Key: InChIKey=KDMVHNWBBNDCOH-YNHILCDOSA-N
• SMILES: [2H]C([2H])(O[Si](C(C)C)(C(C)C)C(C)C)C([2H])(OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)C([2H])([2H])O[Si](C(C)C)(C(C)C)C(C)C