L-Valine Methyl Ester Hydrochloride

CAS: 6306-52-1

Ref. TR-V094325

Produktinformation

• Name: L-Valine Methyl Ester Hydrochloride
• Synonyme: L-Valine, methyl ester, hydrochloride (1:1), L-Valine, methyl ester, hydrochloride (9CI), Valine, methyl ester, hydrochloride, L- (6CI,7CI,8CI), (S)-Valine methyl ester hydrochloride, Methyl (S)-2-amino-3-methylbutanoate hydrochloride, Methyl (S)-valinate hydrochloride, Methyl L-valinate hydrochloride, Methyl valinate hydrochloride, NSC 197198, NSC 22920
• Marke: TRC
• Beschreibung: Applications L-Valine Methyl Ester Hydrochloride is used in the synthesis of Valaciclovir (V085000), the L-Valine ester prodrug of Acyclovir (A192400), orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.References McClean, K. et al.: Tetrahedron Lett., 52, 215 (2011); Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992), Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),

Chemische Eigenschaften

• Molekulargewicht: 167.63
• Formel: C₆H₁₃NO₂·ClH
• Farbe/Form: Neat
• InChl: InChI=1S/C6H13NO2.ClH/c1-4(2)5(7)6(8)9-3;/h4-5H,7H2,1-3H3;1H/t5-;/m0./s1