(2R)-Vildagliptin

CAS: 1036959-27-9

Ref. TR-V305005

Produktinformation

• Name: (2R)-Vildagliptin
• Synonyme: 2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2R)-, (2R)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile, (R)-Vildagliptin
• CAS: 1036959-27-9

Beschreibung

Applications (2R)-Vildagliptin is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4) which can act as a serine exopeptidase. Aside from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 303.40
• Formel: C₁₇H₂₅N₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m1/s1
• SMILES: N#C[C@H]1CCCN1C(=O)CN[C@@]12C[C@@H]3C[C@@H](C[C@@](O)(C3)C1)C2