Vinorelbine N-Methiodide

CAS: 89368-96-7

Ref. TR-V315010

Produktinformation

• Name: Vinorelbine N-Methiodide
• Synonyme: (2R,6R,8S)-8-[(2beta,3beta,4beta,5alpha,12R,19alpha)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-3-(methoxycarbonyl)-1-methylaspidospermidin-15-yl]-4-ethyl-1,3,6,7,8,9-hexahydro-2-methyl-2,6-methano-2H-azecino[4,3-b]indolium Iodide, [2R-(2R*,6R*,8S*)]-8-[(2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-3-(methoxycarbonyl)-1-methylaspidospermidin-15-yl]-4-ethyl-1,3,6,7,8,9-hexahydro-2-methyl-2,6-methano-2H-azecino[4,3-b]indolium Iodide, 3',4'-Didehydro-4'-deoxy-6'-methyl-C'-norvincaleukoblastinium Iodide, Vinorelbine EP Impurity F
• Marke: TRC
• Beschreibung: Applications Vinorelbine N-Methiodide is an impurity of Vinorelbine Ditartrate (V315000); an antineoplastic.References Mathe, G., et al.: Cancer Letters, 27, 285 (1985); Levegue, D., et al.: Clin. Pharmacokinet., 31, 184 (1996); Curran, M.P., et al.: Drugs Aging., 19, 695 (2002)

Chemische Eigenschaften

• Molekulargewicht: 920.87
• Formel: C₄₆H₅₇IN₄O₈
• Farbe/Form: Neat
• InChl: InChI=1S/C46H57N4O8.HI/c1-9-28-20-29-23-45(41(52)56-7,37-31(26-50(5,24-28)25-29)30-14-11-12-15-34(30)47-37)33-21-32-35(22-36(33)55-6)48(4)39-44(32)17-19-49-18-13-16-43(10-2,38(44)49)40(58-27(3)51)46(39,54)42(53)57-8;/h11-16,20-22,29,38-40,47,54H,9-10,17-19,23-26H2,1-8H3;1H/q+1;/p-1/t29-,38-,39+,40+,43+,44+,45-,46-,50-;/m0./s1
• SMILES: CCC1=C[C@H]2C[C@](C(=O)OC)(c3cc4c(cc3OC)N(C)[C@H]3[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)c3[nH]c4ccccc4c3C[N@@+](C)(C1)C2.[I-]