Vortioxetine-d8 Sulfoxide Fumarate

CAS: 1429908-35-9

Ref. TR-V766007

Produktinformation

• Name: Vortioxetine-d8 Sulfoxide Fumarate
• Synonyme: 1-[2-[(2,4-Dimethylphenyl)sulfinyl]phenyl]-piperazine-d8 Fumarate, Piperazine, 1-[2-[(2,4-dimethylphenyl)sulfinyl]phenyl]-, 1-[2-[(2,4-Dimethylphenyl)sulfinyl]phenyl]piperazine, 1-[2-(2,4-Dimethylbenzenesulfinyl)phenyl]piperazine

Beschreibung

Applications Vortioxetine-d8 Sulfoxide Fumarate is labelled Vortioxetine Sulfoxide Fumarate (V766005), an impurity of Vortioxetine (V766000, HBr salt) which is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 322.49 (free base)
• Formel: C₁₈H₁₄D₈N₂OS•xC₄H₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C18H22N2OS.C4H4O4/c1-14-7-8-17(15(2)13-14)22(21)18-6-4-3-5-16(18)20-11-9-19-10-12-20;5-3(6)1-2-4(7)8/h3-8,13,19H,9-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/i9D2,10D2,11D2,12D2
• InChI Key: InChIKey=RAKLYDJAHZCJMS-UHFFFAOYSA-N
• SMILES: CC(N)Cc1ccccc1F.Cl