Z-VAD-FMK

CAS: 187389-52-2

Ref. TR-Z359870

Produktinformation

• Name: Z-VAD-FMK
• Synonyme: 13: PN: WO2005039629 PAGE: 18 claimed protein, 3: PN: WO0158526 SEQID: 3 claimed sequence, 3: PN: WO2011028611 SEQID: 3 unclaimed protein, Z-VAD(OMe)-FMK, Z-Val-Ala-Asp(OMe)-FMK, N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide, (5S,8S,11S)-Methyl 11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oate, <span class="text-smallcaps">L</smallcap>-Alaninamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, N-[(Benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide, N-[(Phenylmethoxy)Carbonyl]-L-Valyl-N-[(1S)-3-Fluoro-1-(2-Methoxy-2-Oxoethyl)-2-Oxopropyl]-L-Alaninamide, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-<smallcap>L</span>-alaninamide, z-VAD-FMK
• CAS: 187389-52-2

Beschreibung

Applications Z-VAD-FMK is a caspase inhibitor that inhibits apoptosis and caspase processing in Jurkat T cells treated with low concentrations of z-FA-CMK.
References Liow, K.Y., Chow, S.C.: Toxicol. App. Pharmacol., 272, 559 (2013)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 467.49
• Formel: C₂₂H₃₀FN₃O₇
• Farbe/Form: White to Off-White Solid
• SMILES: Cc1cc[n+](CCC[N+](C)(C)CCCN)cc1