Produktinformation
- (42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin
- 42-(1-Tetrazolyl)rapamycin
- A 179578
- ABT 578
- Abt 578
- Endeavor
- Rapamycin, 42-deoxy-42-(1H-tetrazol-1-yl)-, (42S)-
- Resolute
- Unii-H4gxr80ize
Applications A tetrazole-containing Rapamycin analog as immunomodulator and useful in the treatment of restenosis and immune and autoimmune diseases.
References Moses, J., et al.: N. Engl. J. Med., 349, 1315 (2003), Ako, J., et al.: J. Am. Coll. Cardiol., 46, 1002 (2005), Wagner, et al.: Bioorg. Med. Chem. Lett., 15, 5340 (2005), Hong, M., et al.: Circulation, 113, 414 (2006),