CAS 100040-31-1

polipéptido inhibidor gástrico humano

Descripción:

El péptido inhibidor gástrico (GIP), también conocido como péptido insulinotrópico dependiente de glucosa, es una hormona péptida producida en las células K del duodeno y el yeyuno en el tracto gastrointestinal. Juega un papel crucial en el metabolismo de la glucosa al estimular la secreción de insulina del páncreas en respuesta a la ingesta de alimentos, particularmente en presencia de glucosa y ácidos grasos. El GIP también inhibe la secreción de ácido gástrico y la motilidad gástrica, de ahí su nombre. La sustancia está compuesta por 42 aminoácidos y es parte de la familia de los incretinas, que son hormonas que mejoran la liberación de insulina. La acción del GIP se media a través de receptores específicos en las células beta pancreáticas, y tiene implicaciones en trastornos metabólicos como la diabetes tipo 2. El número CAS 100040-31-1 identifica de manera única este péptido, facilitando su estudio y aplicación en entornos de investigación y clínicos. En general, el GIP es significativo para entender la interacción entre el sistema digestivo y la regulación metabólica.

Fórmula: C₂₂₆H₃₃₈N₆₀O₆₆S

Sinónimos:

• H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH
• Gip (Human)

Gastric Inhibitory Polypeptide (human)

CAS: 100040-31-1

Gastric inhibitory polypeptide (GIP), an incretin, represents an essential regulator of insulin secretion and glucose homeostasis.

Fórmula: C₂₂₆H₃₃₈N₆₀O₆₆S

Pureza: 97.4%

Forma y color: Whitish Powder

Peso molecular: 4983.6

Ref: 01-4030658

gastric inhibitory polypeptide (human)-Asn-Ile-Thr-Gln-OH

CAS: 100040-31-1

Fórmula: C₂₂₆H₃₃₈N₆₀O₆₆S

Pureza: 95%

Forma y color: Solid

Peso molecular: 4983.5293

Ref: IN-DA01EB06

GIP, human

CAS: 100040-31-1

Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.

Fórmula: C₂₂₆H₃₃₈N₆₀O₆₆S

Pureza: 98%

Forma y color: Solid

Peso molecular: 4983.6

Ref: TM-TP2018

GIP (Human)

CAS: 100040-31-1

GIP is a peptide that is produced by the cells of the small intestine. GIP has been shown to be an inhibitor of insulin secretion and, in turn, may help regulate glucose levels. It also regulates growth hormone release in response to food intake. GIP acts as a ligand for the receptor known as the “gastric inhibitory polypeptide receptor” which is found on pancreatic beta cells and duodenal L-cells. This protein has been shown to activate ion channels and regulate their activity. The GIP receptor is also expressed on certain types of cancer cells, including breast cancer and colorectal cancer. Antibodies have been generated against this protein for use in research tools such as Western blotting or immunohistochemistry.

Fórmula: C₂₂₆H₃₃₈N₆₀O₆₆S

Pureza: Min. 95%

Peso molecular: 4,983.5 g/mol

Ref: 3D-PGR-4178-S

GIP (Human)

CAS: 100040-31-1

GIP (Gastric Inhibitory Polypeptide) is a peptide hormone that belongs to the family of incretin hormones. GIP has been shown to have an insulinotropic effect, which is mediated by its activation of glucose-dependent insulin release from pancreatic β-cells. It also has effects on lipid metabolism and plays a role in the regulation of food intake. GIP is produced by K cells in the ileum and colon and released into the bloodstream following food intake. The binding of GIP to its receptors leads to inhibition of gastric acid secretion, stimulation of gallbladder contraction, increased blood flow to the stomach, relaxation of pyloric sphincter muscles, and inhibition of gastric motility. This product is highly pure (> 98%) with no detectable endotoxin or other microbial contamination.

Fórmula: C₂₂₆H₃₃₈N₆₀O₆₆S

Pureza: Min. 95%

Peso molecular: 4,983.5 g/mol

Ref: 3D-PGR-4178-V