CAS 1013750-77-0

Fórmula: C20H20N4O4S

InChI: InChI=1S/C20H20N4O4S/c1-25-13-6-8-16(26-2)14(10-13)19-21-22-20-24(19)23-15(11-29-20)12-5-7-17(27-3)18(9-12)28-4/h5-10H,11H2,1-4H3

Clave InChI: DZAUSKKPHXFGNN-UHFFFAOYSA-N

SMILES: COC1=CC(=C(C=C1)OC)C2=NN=C3N2N=C(CS3)C4=CC(=C(C=C4)OC)OC

ML-030

CAS: 1013750-77-0

ML-030

Fórmula: C₂₀H₂₀N₄O₄S

Pureza: ≥95%

Peso molecular: 412.46

Ref: 54-BUP10240

ML-030

CAS: 1013750-77-0

Fórmula: C₂₀H₂₀N₄O₄S

Forma y color: Solid

Peso molecular: 412.4622

Ref: IN-DA01CBK9

ML-030

CAS: 1013750-77-0

ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with IC50 ranging from 6.7 to 452 nM.

Fórmula: C₂₀H₂₀N₄O₄S

Pureza: 97.93%

Forma y color: White Solid

Peso molecular: 412.46

Ref: TM-T5496

ML-030

CAS: 1013750-77-0

ML-030 is a red blood cell (RBC) marker to detect the presence of myeloid leukemia. It is an antibody that binds specifically to RBCs and can be used to diagnose the disease by detecting the presence of myeloid cells in the blood. ML-030 has been shown to be effective in identifying cells with a high concentration of myeloid cells, such as those found in acute leukemias. The marker can be used for clinical diagnostics, with a sensitivity of greater than 90% and specificity of more than 95%. This antibody is also suitable for use on bovine serum, which eliminates the need for human serum. Fluorescence analysis can then be performed using ML-030 antibodies to bind the RBCs and identify them under a microscope. This method is capable of achieving high resolution down to 10 microns, which allows for patterning and optical analysis.

Fórmula: C₂₀H₂₀N₄O₄S

Pureza: Min. 95%

Peso molecular: 412.46 g/mol

Ref: 3D-NQB75077

ML-030

Producto controlado

CAS: 1013750-77-0

Applications ML-030 is a triazolothiadiazine that inhibits type 4 cyclic nucleotide phosphodiesterases (PDE4) in a cell-based cyclic nucleotide-gated cation channel biosensor assay.
References Skoumbourdis, A., et al.: Bioorg. Med. Chem. Lett., 18, 1297 (2008); Skoumbourdis, A., et al.: Bioorg. Med. Chem. Lett., 19, 3686 (2009)

Fórmula: C₂₀H₂₀N₄O₄S

Forma y color: Neat

Peso molecular: 412.46

Ref: TR-M425055