CAS 102625-64-9

Sulfuro de pantoprazol

Descripción:

Sulfuro de pantoprazol, con el número CAS 102625-64-9, es un compuesto químico que es un derivado del pantoprazol, un inhibidor de la bomba de protones comúnmente utilizado para tratar la enfermedad por reflujo gastroesofágico (ERGE) y otras condiciones relacionadas con el exceso de ácido estomacal. Este compuesto se caracteriza por su grupo funcional sulfinilo, que contribuye a sus propiedades farmacológicas. Sulfuro de pantoprazol es típicamente un sólido cristalino blanco a blanco sucio, que exhibe baja solubilidad en agua pero mayor solubilidad en disolventes orgánicos. Es conocido por su estabilidad en condiciones ácidas, lo cual es esencial para su función en la inhibición de la secreción de ácido gástrico. El compuesto opera uniendo de manera irreversible la bomba de protones en el revestimiento del estómago, reduciendo así la producción de ácido. Su farmacocinética implica una rápida absorción y metabolismo, principalmente en el hígado, lo que lleva a sus metabolitos activos. Al igual que con muchos productos farmacéuticos, la seguridad y la eficacia son primordiales, y Sulfuro de pantoprazol está sujeto a un escrutinio regulatorio para garantizar que cumpla con los estándares de salud para su uso terapéutico.

Fórmula: C₁₆H₁₅F₂N₃O₃S

InChI: InChI=1/C16H15F2N3O3S/c1-22-13-5-6-19-12(14(13)23-2)8-25-16-20-10-4-3-9(24-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)

Clave InChI: InChIKey=UKILEIRWOYBGEJ-UHFFFAOYSA-N

SMILES: S(CC1=C(OC)C(OC)=CC=N1)C=2NC=3C(N2)=CC(OC(F)F)=CC3

Sinónimos:

• 1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-
• 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-
• 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]thio]-1H-benzimidazole
• 5-(Difluoromethoxy)-2-{[( 3,4 Dimethoxypyridin-2-yl) methyl] thio}-1H-benzimidazolee
• 5-Difluoromethoxy-2-[(3,4-methoxy-2-pyridinylmethyl thio)-1H-benzimidozole
• 5-Diflyoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
• 6-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole
• 6-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole
• H 258/28
• Pantoprazole sulfide
• Pantoprazole thioether
• 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
• 5-(Difluoromethoxy)-2[[(3,4-dimethoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulphanyl}-1H-benzimidazole
• 5-DIFLUOROMETHOXY-2-[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL] THIO-1H-BENZIMIDAZOLE =98%
• 5-(Difluoromethoxy)-2-{[3,4-di
• 5-(DIFLUOROMETHOXY)-2-{[3,4-DIMETHOXY-2-PYRIDINYL)METHYL]THIO}IH-BENZIMIDAZOLE
• 5-DIFLUORMETHOXY-2[(3,4-DIMETHOXY-2-PRIDIXY)METHYLTHIO]-1H-BENZIMIDAZOLE
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)-methyl]-thio}-1H-benzim
• 5-Difluoromethoxy-2-(((3,4-Dimethoxy-2-pyridinyl)methyl)thio)-1H-Benzimidazole (Pantaprazole intermediate)
• 5-Difluoromethoxy-2-{[(3,4-dim
• 5-(DIFLUOROMETHOXY)-2-[[3,4-DIMETHOXY-2-PYRIDINYL)-METHYL]-THIO]-1H-BENZIMIDAZOLE (PANTOPRAZOLE SULPHIDE COMPOUND)
• 5-Difluoromethoxy-2-(3,4-dimethoxy-pyridin-2-ylmethylsulfanyl)-1H-benzoimidazole
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

Pantoprazole Sulfide

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Pureza: >98.0%(T)(HPLC)

Forma y color: Light orange to Light red powder to crystal

Peso molecular: 367.37

Ref: 3B-P2066

Pantoprazole Related Compound B (5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole)

CAS: 102625-64-9

Compounds containing an unfused pyridine ring in the structure, nesoi

Fórmula: C₁₆H₁₅F₂N₃O₃S

Forma y color: Off-White Light Brown Crystalline Powder

Peso molecular: 367.08022

Ref: 45-1494910

1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Pureza: 98%

Forma y color: Solid

Peso molecular: 367.3704

Ref: IN-DA0007YM

Pantoprazole EP Impurity B (Pantoprazole USP Related Compound B, Pantoprazole Sulfide)

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Forma y color: Off-White Solid

Peso molecular: 367.37

Ref: 4Z-P-0111

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

CAS: 102625-64-9

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

Pureza: 98%

Peso molecular: 367.37g/mol

Ref: 54-PC3237

Pantoprazole EP Impurity B

Producto controlado

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Forma y color: Off White

Peso molecular: 367.37

Ref: 86-MM0099.03

Pantoprazole Sulfide

CAS: 102625-64-9

Pantoprazole sulfide, a metabolite of pantoprazole, is formed by CYP2C19 and CYP3A4 enzymes.

Fórmula: C₁₆H₁₅F₂N₃O₃S

Forma y color: Solid

Peso molecular: 367.37

Ref: TM-T37247

Pantoprazole EP Impurity B-d6 (Pantoprazole USP Related Compound B-d6, Pantoprazole Sulfide-d6)

CAS: 102625-64-9

Fórmula: C₁₆H₉D₆F₂N₃O₃S

Peso molecular: 373.41

Ref: 4Z-P-0185

5-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole

CAS: 102625-64-9

Pureza: 95.0%

Peso molecular: 367.3699951171875

Ref: 10-F049541

Pantoprazole EP Impurity B

CAS: 102625-64-9

Fórmula: C₁₆H₁₅F₂N₃O₃S

Peso molecular: 367.37

Ref: ST-EA-CP-P15002

Pantoprazole Sulfide

CAS: 102625-64-9

Impurity Pantoprazole EP Impurity B/ Pantoprazole USP Related Compound B
Applications Pantoprazole Sulfide (Pantoprazole EP Impurity B) is a metabolite of Pantoprazole (P183000), an antiulcerative, gastric pump inhibitor.

Fórmula: C₁₆H₁₅F₂N₃O₃S

Forma y color: Neat

Peso molecular: 367.37

Ref: TR-P183020

Pantoprazole sulphide

CAS: 102625-64-9

Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.

Fórmula: C₁₆H₁₅F₂N₃O₃S

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 367.37 g/mol

Ref: 3D-ID57911