CAS 102691-36-1

N,N,N',N'-tetraisopropil-fosforodiamidita de 2-cianoetilo

Descripción:

El 2-Cianoetilo N,N,N',N'-tetraisopropilfosfordiamidito es un compuesto químico comúnmente utilizado en el campo de la química orgánica, particularmente en la síntesis de oligonucleótidos. Se caracteriza por su estructura de fosforamidito, que presenta un átomo de fósforo unido a dos grupos isopropilo y un grupo cianoetilo, junto con dos átomos de nitrógeno de los grupos funcionales amidito. Este compuesto es típicamente un líquido incoloro a amarillo pálido y es conocido por su estabilidad en condiciones anhidras, lo que lo hace adecuado para su uso en la síntesis de ácidos nucleicos. Su reactividad se atribuye principalmente a la parte de fosforamidito, que puede ser activada para reacciones de acilo con nucleósidos. La presencia del grupo cianoetilo mejora la solubilidad y reactividad del compuesto, facilitando su papel como bloque de construcción en la formación de enlaces fosfodiéster. Se deben observar precauciones de seguridad al manipular este compuesto, ya que puede representar riesgos para la salud si se inhala o ingiere.

Fórmula: C₁₅H₃₂N₃OP

InChI: InChI=1/C15H32N3P/c1-12(2)17(13(3)4)19(11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3

Clave InChI: InChIKey=RKVHNYJPIXOHRW-UHFFFAOYSA-N

SMILES: P(N(C(C)C)C(C)C)(N(C(C)C)C(C)C)OCCC#N

Sinónimos:

• (2-Cyanoethoxy)bis(diisopropylamino)phosphine
• 2-Cyanoethoxybis(N,N-diisopropylamino)phosphine
• 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite
• 2-Cyanoethyl N,N,N,N-tetraisopropyl phosphoramidite
• 2-Cyanoethyl N,N,N,N-tetraisopropylphosphorodiamitide
• 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite
• 2-Cyanoethyl tetraisopropylphosphorodiamidite
• 2-Cyanoethyl-N,N,N¹,N¹-tetraisopropylphosphorodiamidite
• 2-Cyanoethyltetraisopropylphosphorodiamidite
• 2-cyanoethyl N,N,N',N'-tetrapropan-2-ylphosphorodiamidoite
• 3-((Bis(diisopropylamino)phosphino)oxy)propanenitrile
• 3-([Bis[bis(propan-2-yl)amino]phosphanyl]oxy)propanenitrile
• 3-Bis(diisopropylamino)phosphanyloxypropanenitrile
• 3-Bis[di(propan-2-yl)amino]phosphanyloxypropanenitrile
• 3-[Bis(diisopropylamino) phosphinooxy]propanenitrile
• Bis(diisopropylamino)(2-cyanoethoxy)phosphine
• Bis(diisopropylamino)-2-cyanoethoxyphosphane
• P-(2-cyanoethyl)-N,N,N',N'-tetrapropan-2-ylphosphonous diamide
• Phosphorodiamidous acid, N,N,N′,N′-tetrakis(1-methylethyl)-, 2-cyanoethyl ester
• Phosphorodiamidous acid, tetrakis(1-methylethyl)-, 2-cyanoethyl ester
• β-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite
• β-Cyanoethyl-N,N,N′,N′-tetraisopropyldiamidophosphite
• 2-CYANOETHYL-N,N,N'',N''-TETRAISO-PROPYLPHOSPHORAMIDITE(P-REAGENT)
• 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite 98%
• TETRAISOPROPYLPHOSPHORODIAMIDITE
• 5) 2-cyanoethyl-N,N,N',N'-tetraisopropylphosphorodiamidite
• β-Cyanoethyl-N,N,N`,N`-tertraisopropylphosphorodia
• P-REAGENT
• Bis(diisopropylamino)(2-cyanoethoxy)phosphine P-Reagent

2-Cyanoethyl N,N,N',N'-tetra(i-propyl)phosphorodiamidite, min. 98%

CAS: 102691-36-1

2-Cyanoethyl N,N,N',N'-tetra(i-propyl)phosphorodiamidite, min. 98%

Fórmula: (CH₃)₂CHNPOCH₂CH₂CN

Pureza: min. 98%

Forma y color: colorless liq.

Peso molecular: 301.41

Ref: 08-15-0695

Phosphorodiamidous acid, N,N,N',N'-tetrakis(1-methylethyl)-, 2-cyanoethyl ester

CAS: 102691-36-1

Fórmula: C₁₅H₃₂N₃OP

Pureza: 95%

Forma y color: Solid

Peso molecular: 301.4078

Ref: IN-DA00084L

2-Cyanoethyl-N,N,N'',N''-tetraisopropylphosphordiamidite (P-Reagent)

CAS: 102691-36-1

Fórmula: C₁₅H₃₂N₃OP

Pureza: (GC) ≥ 94.0%

Forma y color: Colourless to light yellow liquid

Peso molecular: 301.41

Ref: 7W-GE1115

2-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamidite

CAS: 102691-36-1

2-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamidite

Fórmula: C₁₅H₃₂N₃OP

Pureza: 93%

Forma y color: clear. almost colourless liquid

Peso molecular: 301.41g/mol

Ref: 54-OR5367

2-Cyanoethyl N,N,N',N'-Tetraisopropylphosphordiamidite

CAS: 102691-36-1

Fórmula: C₁₅H₃₂N₃OP

Pureza: >95.0%(GC)(T)

Forma y color: Colorless to Light orange to Yellow clear liquid

Peso molecular: 301.41

Ref: 3B-C2228

3-((Bis(diisopropylamino)phosphino)oxy)-propanenitrile

CAS: 102691-36-1

Pureza: 90.0%

Forma y color: Liquid

Peso molecular: 301.4150085449219

Ref: 10-F213122

2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite

Producto controlado

CAS: 102691-36-1

Stability Explodes When Heated
Applications 2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite (cas# 102691-36-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Fórmula: C₁₅H₃₂N₃OP

Forma y color: Neat

Peso molecular: 301.41

Ref: TR-C982100

1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11

Producto controlado

CAS: 102691-36-1

Applications 1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11 is an intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine.
References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)

Fórmula: C₁₅D₁₁H₈NO₂

Forma y color: Neat

Peso molecular: 256.385

Ref: TR-C982102

2-Cyanoethyl tetraisopropylphosphorodiamidite

CAS: 102691-36-1

2-Cyanoethyl tetraisopropylphosphorodiamidite is widely used for the preparation of modified and unmodified nucleoside phosphoramidites. Nucleoside phosphoramidites are attractive reagents for polymer-supported synthesis of oligonucleotides. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on a protected nucleoside.

Fórmula: C₁₅H₃₂N₃OP

Pureza: (%) Min. 95.0%

Forma y color: Colorless Slightly Yellow Clear Liquid

Peso molecular: 301.42 g/mol

Ref: 3D-FC03165

2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite

CAS: 102691-36-1

2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is a chemical reagent that can be used to synthesize peptides with an amine group at the C-terminus. It reacts with amino acids in aqueous solution to form peptide bonds. This product is suitable for research purposes, and has been widely used in studies of ion channels and protein interactions. 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is also used as an inhibitor in pharmacology research and can be applied to receptor or ligand binding studies.

Fórmula: C₁₅H₃₂N₃OP

Pureza: Min. 95 Area-%

Peso molecular: 301.42 g/mol

Ref: 3D-J-509207