CAS 103335-55-3

Ácido 3-oxo-4-aza-5α-androstano-17β-carboxílico

Descripción:

Ácido 3-oxo-4-aza-5α-androstano-17β-carboxílico, identificado por su número CAS 103335-55-3, es un compuesto sintético que pertenece a la clase de derivados de androstano. Esta sustancia presenta un esqueleto esteroide con un átomo de nitrógeno incorporado en la estructura, lo que la clasifica como un aza-esteroide. La presencia de un grupo cetona en la posición 3 y un grupo funcional ácido carboxílico en la posición 17β contribuyen a su reactividad química y potencial actividad biológica. El compuesto es de interés en la química medicinal, particularmente en el desarrollo de fármacos que apuntan a vías hormonales. Sus modificaciones estructurales pueden influir en su afinidad de unión a los receptores esteroides, convirtiéndolo en un candidato para la investigación en áreas como la regulación hormonal y aplicaciones terapéuticas potenciales. Además, la solubilidad, estabilidad e interacción del compuesto con sistemas biológicos son características importantes que se evaluarían en estudios posteriores para comprender sus propiedades farmacológicas.

Fórmula: C₁₉H₂₉NO₃

InChI: InChI=1S/C19H29NO3/c1-18-9-7-13-11(12(18)4-5-14(18)17(22)23)3-6-15-19(13,2)10-8-16(21)20-15/h11-15H,3-10H2,1-2H3,(H,20,21)(H,22,23)/t11-,12-,13-,14+,15+,18-,19+/m0/s1

Clave InChI: InChIKey=MJXIPHMGYJXKLJ-MLGOENBGSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@H](C(O)=O)CC4)[H])(CC[C@]1(NC(=O)CC2)[H])[H])[H]

Sinónimos:

• (2R,3R,4Bs,6As,7S,9As,9Bs)-4A,6A-Dimethyl-2-Oxo-Hexadecahydro-Indeno[5,4-F]Quinoline-7-Carboxylic Acid
• (4aR,4bS,6aS,7S,9aS,9bS)-4a,6a-Dimethyl-2-Oxo-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-1H-indeno[5,4-f]quinoline-7-Carboxylic acid
• (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-Carboxylic acid
• (4aR,4bS,6aS,7S,9aS,9bS,11aR)-Hexadecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic acid
• (5α,17β)-3-Oxo-4-aza-5α-androstane-17-carboxylic acid
• (5α,17β)-3-Oxo-4-azaandrostane-17-carboxylic acid
• 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, hexadecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-
• 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, hexadecahydro-4a,6a-dimethyl-2-oxo-, [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]-
• 3-Oxo-4-Aza-5-Alpha-Androstane-17-Beta-Carbocylic Acid
• 3-Oxo-4-Azaandrost-5-Een-17-Beta-Carbonzuur
• 3-Oxo-4-aza-5α-androstan-17β-carboxylic acid
• 3-Oxo-4-aza-5α-androstane-17-carboxylic acid
• 3-Oxo-4-aza-5α-androstane-17β-carboxylic acid
• 4-Aza-3-oxo-5α-androstane-17β-carboxylic acid
• 4-Aza-3-oxo-androstane-17β-carboxylic acid
• 4-Aza-5-Androsten-3-One-17-Beta-Carboxylic Acid
• 4-Aza-5-Androsten-3-One-17Beta-Carboxylicacid
• 4-Aza-5-Androsten-3-Oxo-17Β-Carboxylic Acid
• 4-Aza-5A-Androstan-3-One-17Carboxylicacid
• 4-Aza-5Α-Androstan-3-One-17Β-Carboxylic Acid
• 4-Aza-5Α-Androstan-3-Oxo-17Β-Carboxylic Acid
• 4-Azaandrostane-17-carboxylic acid, 3-oxo-, (5α,17β)-

3-Oxo-4-aza-5α-androstan-17β-carboxylic Acid

CAS: 103335-55-3

Fórmula: C₁₉H₂₉NO₃

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 319.45

Ref: 3B-O0514

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-Hexadecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic acid

CAS: 103335-55-3

Fórmula: C₁₉H₂₉NO₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 319.4385

Ref: IN-DA008R10

4-Aza-3-Oxo-5α-Androstane-17β-Carboxylic Acid

CAS: 103335-55-3

4-Aza-3-Oxo-5α-Androstane-17β-Carboxylic Acid

Pureza: 98%

Peso molecular: 319.44g/mol

Ref: 54-OR1027751

3-Oxo-4-aza-5α-androstane-17β-carboxylic Acid

CAS: 103335-55-3

Forma y color: Neat

Ref: 86-MM0415.04

Dutasteride Impurity 3

CAS: 103335-55-3

Fórmula: C₁₉H₂₉NO₃

Peso molecular: 319.45

Ref: 4Z-D-3523

3-Oxo-4-aza-5-alpha-androstane-17-beta-carboxylic acid

CAS: 103335-55-3

3-Oxo-4-aza-5-alpha-androstane-17-beta-carboxylic acid is a versatile building block that can be used in the preparation of complex molecules. This compound is also a reagent, speciality chemical, and useful intermediate for organic synthesis. 3-Oxo-4-aza-5-alpha-androstane-17 beta carboxylic acid has been shown to be useful as a reaction component and scaffold in organic synthesis.

Fórmula: C₁₉H₂₉NO₃

Pureza: Min. 95%

Forma y color: White Clear Liquid

Peso molecular: 319.44 g/mol

Ref: 3D-FO74701

3-Oxo-4-aza-5a-androstan-17b-carboxylic Acid

Producto controlado

CAS: 103335-55-3

Applications 3-Oxo-4-aza-5α-androstan-17β-carboxylic Acid is an impurity in the synthetic process of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.
References Zhang, K. et al.: J. Chin. Pharm. Sci., 16, 233 (2007); Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),

Fórmula: C₁₉H₂₉NO₃

Forma y color: Neat

Peso molecular: 319.44

Ref: TR-O869500

Finasteride Dihydro Carboxylic Acid

CAS: 103335-55-3

Fórmula: C₁₉H₂₉NO₃

Peso molecular: 319.45

Ref: ST-EA-CP-F14007