CAS: 1038915-60-4 - Niraparib

Fórmula: C₁₉H₂₀N₄O

InChI: InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1

Clave InChI: InChIKey=PCHKPVIQAHNQLW-CQSZACIVSA-N

SMILES: O=C(N)C1=CC=CC2=CN(N=C21)C3=CC=C(C=C3)C4CNCCC4

Sinónimos:

• (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
• 2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide
• 2-[4-[(3S)-Piperidin-3-yl]phenyl]indazole-7-carboxamide
• 2H-Indazole-7-carboxamide 2-[4-(3S)-3-piperidinylphenyl]-

2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide

CAS: 1038915-60-4

• Fórmula: C₁₉H₂₀N₄O
• Pureza: 98%
• Forma y color: Solid
• Peso molecular: 320.3883

Niraparib-d5

CAS: 1038915-60-4

• Fórmula: C₁₉H₁₅D₅N₄O
• Peso molecular: 325.43

Niraparib

CAS: 1038915-60-4

• Fórmula: C₁₉H₂₀N₄O
• Peso molecular: 320.40

Niraparib

CAS: 1038915-60-4

• Fórmula: C₁₉H₂₀N₄O
• Forma y color: Neat
• Peso molecular: 320.39

Niraparib

CAS: 1038915-60-4

Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective …

• Fórmula: C₁₉H₂₀N₄O
• Pureza: 98% - 99.91%
• Forma y color: Solid
• Peso molecular: 320.39

(S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide

CAS: 1038915-60-4

• Pureza: 95.0%
• Peso molecular: 320.39599609375

Niraparib

CAS: 1038915-60-4

Applications Niraparib is a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant …

• Fórmula: C₁₉H₂₀N₄O
• Forma y color: Light Yellow
• Peso molecular: 320.39

Niraparib-D5 Major, >90%

CAS: 1038915-60-4

• Fórmula: C₁₉D₅H₁₅N₄O
• Pureza: >90%
• Forma y color: Neat
• Peso molecular: 325.419

MK 4827

CAS: 1038915-60-4

Inhibitor of PARP1 and PARP2 enzymes

• Fórmula: C₁₉H₂₀N₄O
• Pureza: Min. 96 Area-%
• Forma y color: White Powder
• Peso molecular: 320.39 g/mol