CAS 104344-23-2
:Fumarato de bisoprolol
Descripción:
Fumarato de bisoprolol es un bloqueador selectivo del receptor adrenérgico beta-1 que se utiliza principalmente en el manejo de la hipertensión y la insuficiencia cardíaca. Es un polvo cristalino blanco a blanco amarillento que es soluble en agua y metanol, pero menos soluble en disolventes orgánicos como el cloroformo y el éter. La sustancia se caracteriza por su capacidad para reducir la frecuencia cardíaca y la contractilidad miocárdica, lo que la hace efectiva para disminuir la presión arterial y mejorar la función cardíaca. Fumarato de bisoprolol se administra típicamente por vía oral y es conocido por su vida media relativamente larga, lo que permite una dosificación una vez al día. La forma de sal de fumarato mejora su estabilidad y solubilidad, facilitando una mejor absorción en el tracto gastrointestinal. Al igual que otros beta-bloqueadores, puede tener efectos secundarios como fatiga, mareos y bradicardia, y debe usarse con precaución en pacientes con asma o ciertas condiciones cardiovasculares. En general, Fumarato de bisoprolol es un agente terapéutico importante en la medicina cardiovascular, contribuyendo a mejorar los resultados en pacientes con diversas condiciones relacionadas con el corazón.
Fórmula:C18H31NO4C4H4O4
InChI:InChI=1S/C18H31NO4.C4H4O4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
Clave InChI:InChIKey=RZPZLFIUFMNCLY-WLHGVMLRSA-N
SMILES:O(CC(CNC(C)C)O)C1=CC=C(COCCOC(C)C)C=C1.C(=C/C(O)=O)\C(O)=O
Sinónimos:- (2R)-1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol
- 1-(4-((2-Isopropoxyethoxy)methyl)phenoxy)-3-(isopropylamino)propan-2-ol hemifumarate
- 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (2E)-but-2-enedioate (2:1) (salt)
- 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (2E)-but-2-enedioate (salt)
- 1-(Propan-2-Ylamino)-3-(4-{[2-(Propan-2-Yloxy)Ethoxy]Methyl}Phenoxy)Propan-2-Ol
- 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (2E)-2-butenedioate (2:1)
- 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (2E)-2-butenedioate (2:1) (salt)
- 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (E)-2-butenedioate (2:1) (salt)
- Bisoprolol Fumarate
- Bisoprolol fumerate
- Concor
- Detensiel
- Emcor
- Emd 33512
- Emvoncor
- Eurtadal
- Isoten
- Maintate
- Monocor
- Soprol
- Ver más sinónimos
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Pureza (%)
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100
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50
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90
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95
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100
Encontrado 20 productos.
Bisoprolol Hemifumarate
CAS:Fórmula:C18H31NO4C4H4O4Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:383.49BISOPROLOL FOR SYSTEM SUITABILITY CRS
CAS:BISOPROLOL FOR SYSTEM SUITABILITY CRSFórmula:C40H66N2O12Forma y color:Added AddedPeso molecular:766.9582Bisoprolol fumarate
CAS:Bisoprolol fumarateFórmula:(C18H31NO4)2C4H4O4Pureza:99.7%Forma y color:WhitePeso molecular:766.46158BISOPROLOL FUMARATE CRS
CAS:BISOPROLOL FUMARATE CRSFórmula:C40H66N2O12Forma y color:Added AddedPeso molecular:766.9582BISOPROLOL FOR PEAK IDENTIFICATION CRS
CAS:BISOPROLOL FOR PEAK IDENTIFICATION CRSForma y color:Added AddedBisoprolol Fumarate
CAS:Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoiFórmula:(C18H31NO4)2·C4H4O4Forma y color:White PowderPeso molecular:650.45062Bisoprolol (hemifumarate)
CAS:Fórmula:C40H66N2O12Pureza:98%Forma y color:SolidPeso molecular:766.9582Bisoprolol hemifumarate
CAS:Bisoprolol, a selective beta-1 adrenergic receptor antagonist, selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart,Fórmula:C20H33NO6Pureza:98.69% - 99.84%Forma y color:White To Offf-White PowderPeso molecular:383.49Bisoprolol Hemifumarate
CAS:Fórmula:C18H31NO4·5C4H4O4Forma y color:White To Off-White SolidPeso molecular:325.45 0.5*116.07Bisoprolol hemifumarate salt
CAS:Fórmula:C18H31NO40·5C4H4O4Pureza:98.0 - 102.0 %Forma y color:White to almost white powderPeso molecular:383.49(±)-Bisoprolol-d7 Hemifumarate(iso-propyl-d7)
CAS:Pureza:99 atom % DForma y color:White SolidPeso molecular:390.5Bisoprolol Hemifumarate
CAS:Applications A selective β-adrenergic blocker. Used as an antihypertensive.
References Tattersfield, A.E., et al.: Brit. J. Clin. Pharmacol., 18, 343 (1984), Kohli, R.S., et al.: Eur. Heart J., 6, 845 (1985), Zachariah, P.K., et al.: Clin. Ther., 15, 779 (1993),Fórmula:C18H31NO4·C4H4O4Forma y color:NeatPeso molecular:766.9582Bisoprolol hemifumarate
CAS:Producto controladoBisoprolol hemifumarate is a selective beta-1 receptor blocker that has been used in the treatment of high blood pressure, heart failure, and other cardiovascular diseases. It is a prodrug that undergoes enzymatic hydrolysis to bisoprolol in the liver. Bisoprolol hemifumarate has been shown to be effective as an adjunctive therapy for patients with bowel disease and cardiac effects such as lowering blood pressure levels. This drug also has a positive effect on the heart by increasing the levels of natriuretic peptides and decreasing the level of atrial fibrillation (AF). Bisoprolol hemifumarate can be detected in human serum or plasma samples through an analytical method involving liquid chromatography (LC) coupled with tandem mass spectrometry (MS/MS), which can then be analyzed by multivariate logistic regression to control for confounding factors such as age, gender, ethnicity, alcohol intake, and smoking status.
Fórmula:C18H31NO4•(C4H4O4)0Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:383.48 g/molBisoprolol hemifumarate - Bio-X ™
CAS:Producto controladoBisoprolol is a β1- adrenergic antagonist agent that is used to treat hypertension and prevent myocardial infarction. As adrenergic neurotransmitters activate β1-receptors it causes an increase in blood pressure and heart rate. By reducing contractility and the need for oxygen through competitive inhibition of β1-adrenergic receptors, bisoprolol reduces the cardiac workload.Fórmula:C18H31NO4C4H4O4Pureza:Min. 95%Forma y color:PowderPeso molecular:383.48 g/mol
