CAS 104594-70-9

Éster fenetílico del ácido cafeico

Descripción:

Éster fenetílico del ácido cafeico (CAPE) es un compuesto fenólico derivado del ácido cafeico, conocido por sus potenciales propiedades antioxidantes, antiinflamatorias y anticancerígenas. Es un sólido de color marrón amarillento a temperatura ambiente y es soluble en disolventes orgánicos como el etanol y el dimetilsulfóxido, pero tiene una solubilidad limitada en agua. CAPE exhibe una fórmula molecular que refleja su estructura, que incluye un grupo fenetilo unido a la columna vertebral del ácido cafeico. Este compuesto se estudia a menudo por sus actividades biológicas, incluida su capacidad para inhibir varias enzimas y modular vías de señalización, lo que lo convierte en un tema de interés en la investigación farmacológica. CAPE ha sido investigado por sus efectos protectores contra el estrés oxidativo y su posible papel en la prevención de enfermedades crónicas. Además, se reconoce por su capacidad para interactuar con componentes celulares, influyendo en procesos como la apoptosis y la proliferación celular. En general, Éster fenetílico del ácido cafeico es un compuesto significativo en el campo de los productos naturales y la química medicinal, con investigaciones en curso sobre sus aplicaciones terapéuticas.

Fórmula: C₁₇H₁₆O₄

InChI: InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2

Clave InChI: InChIKey=SWUARLUWKZWEBQ-UHFFFAOYSA-N

SMILES: C(=CC(OCCC1=CC=CC=C1)=O)C2=CC(O)=C(O)C=C2

Sinónimos:

• 2-Phenylethyl 3-(3,4-Dihydroxyphenyl)-2-Propenoate
• 2-Phenylethyl 3-(3,4-Dihydroxyphenyl)Prop-2-Enoate
• 2-Phenylethyl caffeate
• 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 2-phenylethyl ester
• 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
• Caffeic acid phenethylester
• Phenethyl Caffeate
• β-Phenylethyl caffeate
• Caffeic acid phenethyl ester
• CAPE

Phenethyl Caffeate

CAS: 104594-70-9

Fórmula: C₁₇H₁₆O₄

Pureza: >98.0%(HPLC)

Forma y color: White to Orange to Green powder to crystal

Peso molecular: 284.31

Ref: 3B-P2088

Phenylethyl 3,4-dihydroxycinnamate, 98+%

CAS: 104594-70-9

Inhibitor of protein tyrosine kinase, and is cytotoxic to cancer cell lines

Fórmula: C₁₇H₁₆O₄

Pureza: 98+%

Peso molecular: 284.31

Ref: 02-J61386

Caffeic acid-phenethyl ester

CAS: 104594-70-9

CAPE is known to have antimitogenic, anticarcinogenic, antiinflammatory, and immunomodulating properties. The molecular basis for these properties seems to be its ability to specifically and potently inhibit the activation of the nuclear transcription factor NF-kappaB.

Fórmula: C₁₇H₁₆O₄

Pureza: 99.4%

Forma y color: White Powder

Peso molecular: 284.31

Ref: 01-4027526

2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

CAS: 104594-70-9

Fórmula: C₁₇H₁₆O₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 284.3065

Ref: IN-DA00HADG

Caffeic acid phenethyl ester

CAS: 104594-70-9

Fórmula: C₁₇H₁₆O₄

Pureza: ≥ 98.0%

Forma y color: White to yellow crystalline powder

Peso molecular: 284.31

Ref: 7W-GK2776

Caffeic Acid Phenethyl Ester

CAS: 104594-70-9

Caffeic Acid Phenethyl Ester

Pureza: ≥98%

Peso molecular: 284.31g/mol

Ref: 54-BUP17813

Caffeic acid-phenylethyl ester

CAS: 104594-70-9

Fórmula: C₁₇H₁₆O₄

Forma y color: Neat

Peso molecular: 284.31

Ref: 04-C10934730

Caffeic acid phenethyl ester

CAS: 104594-70-9

Fórmula: C₁₇H₁₆O₄

Pureza: 95%~99%

Peso molecular: 284.311

Ref: BP-SBP03991

Caffeic Acid Phenethyl Ester

CAS: 104594-70-9

CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.

Fórmula: C₁₇H₁₆O₄

Pureza: 99.18% - 99.35%

Forma y color: Less Transparent Liquid Colorless Transparent Liquid

Peso molecular: 284.31

Ref: TM-T6429

Caffeic acid phenethyl ester

CAS: 104594-70-9

Caffeic acid phenethyl ester

Fórmula: C₁₇H₁₆O₄

Pureza: 98% (nmr) (Typical Value in Batch COA)

Forma y color: off-white solid

Peso molecular: 284.31g/mol

Ref: 54-BIB6022

Caffeic Acid Phenethyl Ester

CAS: 104594-70-9

Applications Cytotoxic agent against cancer cell lines. Inhibitor of ornithine decarboxylase and protein tyrosine kinase. Found to be a specific inhibitor of the nuclear transcription factor, NF-kB. It has also been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation.
References Grunberger, D., et al.: Experientia, 44, 230 (1988), Fesen, M.R., et al.: Biochem. Pharmacol., 48, 595 (1994), Su, Z.Z., et al.: Cancer Res., 54, 1865 (1994), Zheng, Z.S., et al.: Oncol. Res., 7, 445 (1995), Mirzoeva, O.K. and Calder, P.C.: Essent. Fatty Acids, 55, 441 (1996)

Fórmula: C₁₇H₁₆O₄

Forma y color: Neat

Peso molecular: 284.31

Ref: TR-C080050

Caffeic acid phenethyl ester

CAS: 104594-70-9

Caffeic acid phenethyl ester (CAPE) is an active phenolic compound found in honeybee propolis that has the potential to downregulate inflammation in mammals. Studies demonstrated that CAPE specifically inhibits the protein complex NF-κB - a key player in inflammation, associated with the pathogenesis of chronic inflammatory diseases. Moreover, CAPE inhibits the activity of the enzyme cyclooxygenase and the production of nitric oxide by macrophages, also responsible for inflammation. By acting on T cells, CAPE can reduce the production of pro-inflammatory cytokines and increase the production of anti-inflammatory ones, leading to a less overwhelming immune response to allergens.

Fórmula: C₁₇H₁₆O₄

Pureza: Min. 98.0 Area-%

Peso molecular: 284.31 g/mol

Ref: 3D-C-1400

PHENETHYL CAFFEATE

CAS: 104594-70-9

Pureza: 97%

Peso molecular: 284.3110046

Ref: 10-F814395

Phenethyl 3-(3,4-dihydroxyphenyl)acrylate

CAS: 104594-70-9

Fórmula: C₁₇H₁₆O₄

Pureza: 95.0%

Forma y color: No data available.

Peso molecular: 284.311

Ref: 10-F212797