CAS 10540-29-1
:Tamoxifeno
Descripción:
Tamoxifeno es un compuesto sintético no esteroidal utilizado principalmente en el tratamiento y prevención del cáncer de mama positivo para receptores de estrógeno. Funciona como un modulador selectivo de receptores de estrógeno (SERM), exhibiendo propiedades tanto estrogénicas como antiestrogénicas dependiendo del tejido objetivo. Químicamente, Tamoxifeno se caracteriza por su estructura de bifenilo, que le permite unirse a los receptores de estrógeno, inhibiendo así los efectos del estrógeno en el tejido mamario mientras que potencialmente ejerce efectos similares al estrógeno en otros tejidos, como el hueso y el endometrio. Su fórmula molecular es C26H29NO, y tiene una lipofilia relativamente alta, lo que ayuda en su absorción y distribución en el cuerpo. Tamoxifeno se administra típicamente por vía oral y es conocido por sus efectos secundarios, que pueden incluir sofocos, riesgo de eventos tromboembólicos y posibles cambios endometriales. Debido a su mecanismo de acción, Tamoxifeno ha sido un pilar en la terapia del cáncer de mama, particularmente para mujeres premenopáusicas, y continúa siendo objeto de investigación por sus implicaciones más amplias en el tratamiento y prevención del cáncer.
Fórmula:C26H29NO
InChI:InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
Clave InChI:InChIKey=NKANXQFJJICGDU-QPLCGJKRSA-N
SMILES:C(=C(/CC)\C1=CC=CC=C1)(\C2=CC=C(OCCN(C)C)C=C2)/C3=CC=CC=C3
Sinónimos:- (Z)-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine
- 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine
- 2-{4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
- 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
- 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt)
- Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-
- Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-
- Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethyl-
- Ethylamine, 2-[p-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-
- Genox
- Ici 47699
- Kessar
- Mammaton
- Nolvadex
- Nolvadex-D
- Novaldex
- Tamoxen
- Tamoxifen Free Base
- Tamoxifen and its salts
- Tamoxifene
- Tamoxifeno
- Z-Tamoxifen
- Ver más sinónimos
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Encontrado 12 productos.
Tamoxifen Citrate
CAS:Fórmula:C26H29NO·C6H8O7Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:563.65Tamoxifen, 98%
CAS:<p>Tamoxifen, 10540-29-1, is an antineoplastic agent that acts by competitively binding estrogen receptors to reduce DNA synthesis. Learn more at Thermo Fisher Scientific.</p>Fórmula:C26H29NOPureza:98%Forma y color:Powder, White to pale creamPeso molecular:371.52Tamoxifen
CAS:<p>Tamoxifen is an orally active selective estrogen receptor modulator (SERM) that acts as an estrogen antagonist in breast cells and an agonist in bone, liver, and uterine cells. It can be used to induce gene knockout and liver injury models in mice, and also exhibits multiple biological activities, including activation of Hsp90, induction of autophagy and apoptosis, and inhibition of EBOV and MARV viral infections.</p>Fórmula:C26H29NOPureza:98.46% - 99.92%Forma y color:Fine Off-White Crystalline PowderPeso molecular:371.51Tamoxifen
CAS:Fórmula:C26H29NOPureza:≥ 99.0%Forma y color:White to off-white crystalline powderPeso molecular:371.52Tamoxifen EP Impurity F-d5 HCl (N-Desmethyl Tamoxifen-d5 HCl)
CAS:Fórmula:C25H22D5NO·HClPeso molecular:362.53 36.46Tamoxifen
CAS:Producto controlado<p>Estrogen receptor modulator; protein kinase C inhibitor</p>Fórmula:C26H29NOPureza:Min. 90%Forma y color:White PowderPeso molecular:371.51 g/molTamoxifen - Bio-X ™
CAS:Producto controlado<p>Tamoxifen is used as an antineoplastic agent in the treatment of breast cancer. Tamoxifen has been shown to be a competitive antagonist at the estrogen receptor, preventing estrogen from binding and activating it. <br>Tamoxifen is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Fórmula:C26H29NOPureza:(%) Min. 95%Forma y color:PowderPeso molecular:371.51 g/molTamoxifen (1 mg/mL in Methanol)
CAS:Producto controladoFórmula:C26H29NOForma y color:ColourlessPeso molecular:371.52trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
CAS:Producto controlado<p>2,4-Diphenyl-1-butenylphenoxyN,N-dimethylethylamine (2DPB) is a natural compound that has been shown to have cytotoxic effects in breast cancer cell lines. 2DPB is a selective estrogen receptor modulator (SERM) that binds to the estrogen receptor and alters its shape, which blocks the binding of estrogens. 2DPB has also been shown to have antiestrogenic activity in human breast cancer tissues. The drug has been studied as a potential treatment for breast cancer because it targets the estrogen receptor and prevents the growth of tumor cells in preclinical models. This drug is currently being investigated for its effects on tumor suppression and prevention of recurrence.</p>Fórmula:C26H29NOPureza:Min. 98.0 Area-%Peso molecular:371.51 g/mol
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