CAS 105454-04-4

7-Epitaxol

Descripción:

7-Epitaxol, con el número CAS 105454-04-4, es un derivado sintético del compuesto natural paclitaxel, conocido por sus propiedades anticancerígenas. Este compuesto se caracteriza por su compleja estructura policíclica, que incluye un núcleo de taxano que es esencial para su actividad biológica. 7-Epitaxol exhibe un mecanismo de acción similar al del paclitaxel, funcionando principalmente como un estabilizador de microtúbulos, inhibiendo así la división celular y promoviendo la apoptosis en células cancerosas. Su eficacia se evalúa a menudo en varios tipos de cáncer, incluidos el cáncer de mama y de ovario. El compuesto se administra típicamente en una formulación que mejora su solubilidad y biodisponibilidad, ya que es poco soluble en agua. Además, 7-Epitaxol puede tener diferentes propiedades farmacocinéticas en comparación con el paclitaxel, lo que podría llevar a variaciones en los resultados terapéuticos y efectos secundarios. La investigación en curso tiene como objetivo comprender mejor su rango completo de actividades biológicas y aplicaciones potenciales en la terapia del cáncer.

Fórmula: C₄₇H₅₁NO₁₄

InChI: InChI=1/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32+,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1

Clave InChI: InChIKey=RCINICONZNJXQF-LYTKHFMESA-N

SMILES: O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)O)=O)C5)[H]

Sinónimos:

• (2alpha,5beta,7alpha,10beta,13alpha)-4,10-bis(acetyloxy)-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
• 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
• 7-Epipaclitaxel
• 7-epi-Paclitaxel
• 7-epi-Taxol
• Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (alphaR,betaS)-
• Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR- (2aalpha,4alpha,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))-
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4α,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
• Epitaxol
• 7-Epitaxol
• Paclitaxel EP impurity E
• 7-EpipaclitaxelQ: What is
• 7-EPIPACLITAXEL; 7-EPITAXOL; 7-EPI-PACLITAXEL; EPITAXOL
• 7-Epi Paclitaxel (Paclitaxel EP Impurity E)
• Paclitaxel Impurity 5（Paclitaxel EP Impurity E）
• Paclitaxel Impurity E (7-epi Paclitaxel)
• 7-Epipaclitaxel Q: What is the storage condition of
• 7-Epipaclitaxel, 98%, from Taxus chinensis (Pilg.) Rehder
• Propanedioicacid,2-(2-propyn-6-yl)-,diethylester
• Paclitaxel Impurity E
• Paclitaxel 7-Epi-Impurity
• 7-Epipaclitaxel(crude)
• 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid derivative
• 7-Epipaclitaxel Q: What is the CAS Number of
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4α,4aβ,6β
• Paclitaxel EP Impurity E (7-epi Paclitaxel)
• EPITAXOL, 7-
• 7-epi-Paclitaxel(7-Epitaxol)
• Paclitaxel Impurity Ⅲ:(7-Epi-Paclitaxel)
• Benzenepropanoicacid,beta-(benzoylaMino)-alpha-hydroxy-,6,12B-bis(acetyloxy)-12-(benzoyloxy)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,11-dihydroxy-4A,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-ylester,(2ar-(
• 7-Epipaclitaxel, froM Taxus chinensis
• Paclitaxel Impurity E (7-Diverse Taxol)
• inhibit,Microtubule/Tubulin,7 epi Taxol,7epiTaxol,Inhibitor

7-epi-Taxol

CAS: 105454-04-4

7-epi-Taxol

Pureza: ≥98%

Peso molecular: 853.91g/mol

Ref: 54-BUP06028

Paclitaxel EP Impurity E (7-epi Paclitaxel)

CAS: 105454-04-4

Fórmula: C₄₇H₅₁NO₁₄

Forma y color: Pale Pink Solid

Peso molecular: 853.92

Ref: 4Z-P-2815

7-Epitaxol

CAS: 105454-04-4

Fórmula: C₄₇H₅₁NO₁₄

Pureza: ≥ 98.0%

Forma y color: White to off-white powder

Peso molecular: 853.92

Ref: 7W-GY8649

7-Epitaxol

CAS: 105454-04-4

Fórmula: C₄₇H₅₁NO₁₄

Pureza: 95%~99%

Peso molecular: 853.918

Ref: BP-BP0098

7-epi-Paclitaxel

Producto controlado

CAS: 105454-04-4

Fórmula: C₄₇H₅₁NO₁₄

Forma y color: Neat

Peso molecular: 853.91

Ref: 86-MM1489.08

7-epi-Taxol

CAS: 105454-04-4

Peso molecular: 853.918

Ref: 10-F986733

7-epi-Taxol

CAS: 105454-04-4

1.

Fórmula: C₄₇H₅₁NO₁₄

Pureza: 99.32% - 99.93%

Forma y color: Solid

Peso molecular: 853.91

Ref: TM-T3S2372

7-Epi Paclitaxel

Producto controlado

CAS: 105454-04-4

Fórmula: C₄₇H₅₁NO₁₄

Forma y color: Off-White

Peso molecular: 853.91

Ref: TR-E588630

7-epi-Taxol

CAS: 105454-04-4

Paclitaxel is an anticancer drug that belongs to the class of taxanes. Paclitaxel binds to cell membranes and interferes with cell division by preventing the polymerization of microtubule proteins. This drug can be prepared by high-performance liquid chromatography (HPLC) and has minimal toxicity in humans, but is highly toxic in rats. Paclitaxel also inhibits glucose uptake in breast cancer cells, leading to significant cytotoxicity. It has inhibitory properties against toll-like receptor 4, which may contribute to its anti-inflammatory effects.

Fórmula: C₄₇H₅₁NO₁₄

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 853.91 g/mol

Ref: 3D-IM22711

Paclitaxel EP Impurity E

CAS: 105454-04-4

Fórmula: C₄₇H₅₁NO₁₄

Peso molecular: 853.92

Ref: ST-EA-CP-P36005