CAS 105462-24-6

Risedronato

Descripción:

Risedronato es un medicamento bisfosfonato que se utiliza principalmente para tratar la osteoporosis y otras condiciones que conducen a la pérdida ósea. Funciona inhibiendo la resorción ósea mediada por osteoclastos, aumentando así la densidad mineral ósea y reduciendo el riesgo de fracturas. La fórmula química de Risedronato es C7H10N2O7P2, y presenta un grupo piridinilo, que contribuye a su actividad biológica. Risedronato se administra típicamente por vía oral y es conocido por su relativamente alta biodisponibilidad en comparación con otros bisfosfonatos. Se caracteriza por su estabilidad en condiciones fisiológicas y su capacidad para unirse a la hidroxiapatita en el tejido óseo. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales, y es importante que los pacientes permanezcan en posición vertical durante un período después de tomar el medicamento para minimizar la irritación esofágica. Risedronato a menudo se prescribe en varios regímenes de dosificación, incluyendo opciones diarias, semanales o mensuales, dependiendo del escenario clínico específico. En general, Risedronato desempeña un papel significativo en el manejo de la salud ósea, particularmente en mujeres posmenopáusicas e individuos en riesgo de osteoporosis.

Fórmula: C₇H₁₁NO₇P₂

InChI: InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15)

Clave InChI: InChIKey=IIDJRNMFWXDHID-UHFFFAOYSA-N

SMILES: C(CC=1C=CC=NC1)(P(=O)(O)O)(P(=O)(O)O)O

Sinónimos:

• (1-Hydroxy-2-(3-pyridyl)ethylidene)diphosphonic acid
• 1-Hydroxy-2-(3-pyridinyl)ethane-1,1-diphosphonic acid
• 1-Hydroxy-2-(3-pyridinyl)ethylidene bisphosphonic acid
• 1-Hydroxy-2-(3-pyridyl)ethylidene-1,1-diphosphonic acid
• 1-Hydroxy-2-pyrid-3-ylethylidene-1,1-bisphosphonic acid
• Acide risedronique
• Acide risedronique [INN-French]
• Acido risedronico
• Acido risedronico [INN-Spanish]
• Acidum risedronicum
• Acidum risedronicum [INN-Latin]
• Benet
• Bph 2
• Hsdb 7326
• Ne 58019
• P,P′-[1-Hydroxy-2-(3-pyridinyl)ethylidene]bis[phosphonic acid]
• Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-
• Phosphonic acid, P,P′-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis-
• Risedronate
• Risedronic acid [INN:BAN]
• Unii-Km2Z91756Z
• [1-Hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid
• [1-Hydroxy-2-(Pyridin-3-Yl)Ethane-1,1-Diyl]Bis(Phosphonic Acid)

Monosodium Risedronate Hemipentahydrate

CAS: 105462-24-6, 115436-72-1, 329003-65-8

Fórmula: C₇H₁₀NNaO₇P₂H₂O

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 350.13

Ref: 3B-M2289

Risedronic Acid

CAS: 105462-24-6

Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.

Fórmula: C₇H₁₁NO₇P₂

Pureza: 99.85% - 99.87%

Forma y color: White Crystalline Powder

Peso molecular: 283.11

Ref: TM-T0379

[1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid

CAS: 105462-24-6

Fórmula: C₇H₁₁NO₇P₂

Pureza: 97%

Forma y color: Solid

Peso molecular: 283.1123

Ref: IN-DA00HANG

Risedronic Acid

CAS: 105462-24-6

Risedronic Acid

Pureza: 98%

Peso molecular: 283.11g/mol

Ref: 54-OR1014894

Risedronic Acid

CAS: 105462-24-6

Fórmula: C₇H₁₁NO₇P₂

Forma y color: White To Off-White Solid

Peso molecular: 283.11

Ref: 4Z-R-054

Risedronic Acid

CAS: 105462-24-6

Risedronic Acid

Pureza: ≥98%

Peso molecular: 283.11g/mol

Ref: 54-BUP17831

Risedronate

CAS: 105462-24-6

Fórmula: C₇H₁₁NO₇P₂

Peso molecular: 283.11

Ref: 7W-GP6400

Risedronic Acid

CAS: 105462-24-6

Forma y color: Neat

Ref: 86-MM0777.09

Risedronic Acid

Producto controlado

CAS: 105462-24-6

Applications Risedronic Acid is a pyridinyl biphosphonate bone resorption inhibitor.
References Mortensen, L., et al.: J. Clin. Endocrinol. Metab., 83, 396 (1998); Harris, S.T., et al.: J. Am. Med. Assoc., 282, 1344 (1999); Boiser, S., et al.: Cancer Res., 60, 2949 (2000)

Fórmula: C₇H₁₁NO₇P₂

Forma y color: White To Off-White

Peso molecular: 283.11

Ref: TR-R521505

Risedronic acid monohydrate

CAS: 105462-24-6

Risedronic acid monohydrate is a bisphosphonate that inhibits bone resorption by inhibiting the activity of osteoclasts. It is used to treat postmenopausal women with osteoporosis and bowel disease, as well as to prevent bone loss in men with prostate cancer. Risedronic acid monohydrate has been shown to be more effective than alendronate for decreasing bone mineral density in women with breast cancer who have undergone chemotherapy. Risedronic acid monohydrate binds to the active site of the enzyme polymerase chain reaction (PCR) and blocks DNA synthesis, preventing the formation of new cells. Risedronic acid monerate also binds to the active site of nonsteroidal anti-inflammatory drugs (NSAIDs), thereby blocking their ability to inhibit cyclooxygenase enzymes, which are responsible for prostaglandin synthesis. This leads to reduced inflammation and pain.

Fórmula: C₇H₁₁NO₇P₂·H₂O

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 301.13 g/mol

Ref: 3D-FH61572

Risedronic acid

CAS: 105462-24-6

Fórmula: C₇H₁₁NO₇P₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 283.113

Ref: 10-F304322

Risedronic Acid-d4, 13C

Producto controlado

CAS: 105462-24-6

Fórmula: CC₆D₄H₇NO₇P₂

Forma y color: Neat

Peso molecular: 288.13

Ref: TR-R521507