CAS 1070773-09-9

Fórmula: C23H20N6O3

InChI: InChI=1S/C23H20N6O3/c1-31-17-7-3-15(4-8-17)11-28-14-26-19-20-22(25-13-24-21(19)28)29(23(30)27-20)12-16-5-9-18(32-2)10-6-16/h3-10,13-14H,11-12H2,1-2H3

Clave InChI: COUMZXFUZDBRCZ-UHFFFAOYSA-N

SMILES: COC1=CC=C(C=C1)CN2C=NC3=C2N=CN=C4C3=NC(=O)N4CC5=CC=C(C=C5)OC

RK-33

CAS: 1070773-09-9

Fórmula: C₂₃H₂₀N₆O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 428.4433

Ref: IN-DA01ENVM

RK33

CAS: 1070773-09-9

RK33

Fórmula: C₂₃H₂₀N₆O₃

Pureza: ≥95%

Peso molecular: 428.44

Ref: 54-BUP05962

RK 33-d6

CAS: 1070773-09-9

Fórmula: C₂₃H₁₄D₆N₆O₃

Peso molecular: 434.49

Ref: 4Z-R-161002

RK 33

CAS: 1070773-09-9

Fórmula: C₂₃H₂₀N₆O₃

Peso molecular: 428.45

Ref: 4Z-R-161001

RK-33

CAS: 1070773-09-9

3,7-Bis(4-methoxybenzyl)-3,7-dihydro-2H-diimidazo[4,5-d:4',5'-f][1,3]diazepin-2-one

Fórmula: C₂₃H₂₀N₆O₃

Pureza: 98%

Peso molecular: 428.44

Ref: IN-DG764708

RK33

CAS: 1070773-09-9

"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."

Fórmula: C₂₃H₂₀N₆O₃

Pureza: 99.04% - 99.72%

Forma y color: Solid

Peso molecular: 428.44

Ref: TM-T6970

RK33

CAS: 1070773-09-9

Ref: BE-RMCR098000

RK 33

Producto controlado

CAS: 1070773-09-9

Applications RK 33 is an inhibitor of DDX3, an ATP-dependent RNA helicase (1). Aberrant regulation of DDX3 is related to various diseases such as prostate and breast cancer (2). RK 33 was shown to decrease proliferation of prostate cancer cells and induced a G1 phase cell-cycle arrest (2).
References (1) Botlagunta, M. et al.: PLoS One. 6, e17563 (2011) (2) Xie, M., et al.: Cancer Res. 76, 6340 (2016)

Fórmula: C₂₃H₂₀N₆O₃

Forma y color: Neat

Peso molecular: 428.44

Ref: TR-R545500

RK-33

CAS: 1070773-09-9

RK-33 is a small molecule inhibitor, which is synthesized as a chemical compound. It functions by targeting and inhibiting the activity of DDX3, a DEAD-box RNA helicase, which plays a crucial role in the modulation of RNA biogenesis and translation processes. By interfering with DDX3, RK-33 disrupts processes essential for the proliferation of certain cancer cells, making it a significant focus in cancer research.

Fórmula: C₂₃H₂₀N₆O₃

Pureza: Min. 95%

Peso molecular: 428.44 g/mol

Ref: 3D-VSB77309