CAS 107444-51-9

péptido similar al glucagón I fragmento 7-36*amida humano

Descripción:

El fragmento 7-36 amida del péptido similar al glucagón-1 (GLP-1) es una hormona péptida que desempeña un papel crucial en el metabolismo de la glucosa y la regulación del apetito. Se deriva del gen proglucagón y es secretado principalmente por las células L intestinales en respuesta a la ingesta de alimentos. Este péptido consta de 30 aminoácidos y es conocido por su capacidad para estimular la secreción de insulina de manera dependiente de la glucosa, ayudando así a reducir los niveles de azúcar en sangre. Además, el fragmento 7-36 amida de GLP-1 inhibe la liberación de glucagón, ralentiza el vaciamiento gástrico y promueve la saciedad, lo que lo convierte en un objetivo para el tratamiento de la diabetes y el manejo de la obesidad. La forma amida indica que el C-terminal del péptido está amidado, lo cual es importante para su actividad biológica y estabilidad. Debido a sus efectos fisiológicos, el GLP-1 y sus análogos se utilizan en aplicaciones terapéuticas, particularmente en el manejo de la diabetes mellitus tipo 2. El número CAS 107444-51-9 identifica de manera única este péptido específico en bases de datos químicas, facilitando la investigación y el desarrollo en farmacología y bioquímica.

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Sinónimos:

• Glucagon-Like Peptide 1 (7-36) amide (human)
• H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
• Glp-1(7-36)
• Glucagon-Like Peptide I Fragment 7-36 Amide Human

Glucagon-Like Peptide-1 (7-36) amide, human

CAS: 107444-51-9

For cellular and molecular biology applications

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Forma y color: Lyophilized Powder, White

Peso molecular: 3297.7

Ref: 02-J66197

GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)

CAS: 107444-51-9

GLP-1 (7-36) amide is secreted from the lower small intestine and shows a strong insulinotropic effect. GLP-1 (7-36) amide is considered as the most important incretin hormone. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells. Considerable interest has focused on the development of this peptide as a therapeutic strategy for non-insulin-dependent (type 2 ) diabetes mellitus and associated neuropathy.

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Pureza: > 96%

Forma y color: White

Peso molecular: 3297.68

Ref: 01-4030663

GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

CAS: 107444-51-9

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 3297.6297

Ref: IN-DA008R5L

GLP-1(7-36)

CAS: 107444-51-9

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Pureza: 95%~99%

Forma y color: White to Off-white Powder

Peso molecular: 3297.63

Ref: BP-BPPG034

GLP-1(7-36), amide

CAS: 107444-51-9

GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.Cost-effective and quality-assured.

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Pureza: 99.85%

Forma y color: White Powder

Peso molecular: 3297.63

Ref: TM-T3984

GLP-1 (7-36) amide

CAS: 107444-51-9

This is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide.  This peptide, human GLP-1 (7–36), shares the same sequence with preproglucagon (78-107), amide, human.

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Forma y color: Powder

Peso molecular: 3,297.63 g/mol

Ref: 3D-CRB1000250

Glucagon-like Peptide 1 (Human, 7-36 Amide)

CAS: 107444-51-9

Glucagon-like peptide 1 (GLP-1) is a peptide hormone that belongs to the glucagon family. It is a 36 amino acid polypeptide and is naturally synthesized in the ileum of humans, pigs, and cows. GLP-1 is an activator of ion channels, which are protein structures that regulate the flow of ions across cell membranes. This hormone also has been shown to inhibit the activity of protein interactions at the cell membrane or ligand binding to receptors.

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Pureza: Min. 95%

Peso molecular: 3,297.6 g/mol

Ref: 3D-PGL-4344-V

Glucagon-Like Peptide I (7-36), amide, human

CAS: 107444-51-9

Custom research peptide; min purity 95%.

Fórmula: C₁₄₉H₂₂₉N₄₀O₄₅

Pureza: Min. 95%

Peso molecular: 3,297.7 g/mol

Ref: 3D-PG16978

Glucagon-Like Peptide I (7-36), amide, human

CAS: 107444-51-9

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Peso molecular: 3,297.7 g/mol

Ref: 3D-PP50623

Glucagon-like peptide 1 (7-36) amide

CAS: 107444-51-9

Glucagon-like peptide 1 (7-36) amide is a peptide hormone produced by the ileum and colon of the small intestine in response to food intake. It stimulates insulin release from the pancreas, inhibits glucagon secretion, and slows gastric emptying. GLP-1 is also a potent regulator of glucose homeostasis. The GLP-1 analogues are used for treatment of type 2 diabetes mellitus. These analogues are either injected or taken orally and mimic the effect of natural GLP-1 on blood sugar regulation and appetite control. The long duration of action means that daily injections or multiple oral doses are required to maintain therapeutic levels.

Fórmula: C₁₄₉H₂₂₆N₄₀O₄₅

Pureza: Min. 95%

Peso molecular: 3,297.63 g/mol

Ref: 3D-FG109975