CAS 108321-42-2

Sulfato de geneticina

Descripción:

Sulfato de geneticina, también conocido como G418, es un antibiótico aminoglucósido que se utiliza principalmente en biología molecular para la selección de células genéticamente modificadas. Es efectivo contra una amplia gama de bacterias y es particularmente conocido por su capacidad para inhibir la síntesis de proteínas al unirse a la subunidad ribosómica 30S. Este compuesto se utiliza a menudo en cultivos celulares para seleccionar células que han sido transfectadas con plásmidos que contienen un marcador genético para la resistencia a Geneticin. La forma sulfato mejora su solubilidad en soluciones acuosas, lo que lo hace adecuado para aplicaciones de laboratorio. Geneticin se utiliza típicamente a concentraciones que varían según el tipo de célula y las condiciones experimentales. Es importante manejar Sulfato de geneticina con cuidado, ya que puede ser tóxico para las células no resistentes. Además, debido a sus propiedades antibióticas, es crucial considerar los efectos potenciales sobre la flora microbiana en los montajes experimentales. En general, Sulfato de geneticina es una herramienta valiosa en la ingeniería genética y la investigación en biología celular.

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

InChI: InChI=1S/C20H40N4O10.H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;(H2,1,2,3,4)/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+;/m1./s1

Clave InChI: InChIKey=QNQZPJLBGRQFDD-ZMSORURPSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@]([C@@H](C)O)([C@@H](O)[C@H](O)[C@H]2N)[H])[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3.S(=O)(=O)(O)O

Sinónimos:

• (2R,3S,4R,5R,6S)-5-amino-6-[(1S,2R,4S,6R)-4,6-diamino-3-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-2-(1-hydroxyethyl)tetrahydropyran-3,4-diol
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt)
• ANTIBIOTIC G-418 Sulfate
• G-418 Sulfate
• G-418 Sulphate
• G418 Disulfate Cell Culture Tested
• G418 Disulfate Plant Cell Culture Tested
• G418 Solution
• G418 Sulfate
• Geneticin sulfate
• Sulfuric Acid
• D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)

G418 disulfate, Cell Culture Reagent

CAS: 108321-42-2

G418 disulfate, cell culture reagent, 108321-42-2, is an aminoglycoside antibiotic structurally related to gentamicin B1. Learn more at Thermo Fisher Scientific.

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Forma y color: White, Powder

Peso molecular: 692.70

Ref: 02-J62671

G418 disulfate, 50mg/ml solution

CAS: 108321-42-2

G418 disulfate, 108321-42-2, is an aminoglycoside antibiotic structurally related to gentamicin B1 suitable for cell culture. Learn more at Thermo Fisher Scientific.

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Forma y color: Liquid, Clear colorless

Peso molecular: 692.70

Ref: 02-J63871

G 418 Disulfate Salt

CAS: 108321-42-2

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 692.7094

Ref: IN-DA00HB58

G-418 Disulphate

CAS: 108321-42-2

G-418 Disulphate

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Pureza: 99.9%

Forma y color: solid

Peso molecular: 692.71g/mol

Ref: 54-BIG0175

G-418 Sulphate solution 50mg/ml

CAS: 108321-42-2

G-418 Sulphate solution 50mg/ml

Forma y color: Solution

Peso molecular: 594.63088g/mol

Ref: 54-BIG0176

G418 disulphate salt

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Pureza: ≥ 720μg/mg

Forma y color: White to almost white powder

Peso molecular: 692.71

Ref: 7W-GA2946

G418 disulphate salt, 10% solution in water

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Forma y color: Clear, colourless liquid

Peso molecular: 692.71

Ref: 7W-GP6404

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate

Pureza: ≥98%

Peso molecular: 692.71g/mol

Ref: 54-BUP18758

G-418.Sulfate Solid

CAS: 108321-42-2

M01801 - G-418.Sulfate Solid

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Pureza: >90.0%(HPLC)(N)

Forma y color: Solid

Peso molecular: 692.7

Ref: 10-M01801

Geneticin Disulfate

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Peso molecular: 496.56 2*98.07

Ref: 4Z-G-215001

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in cells.

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Pureza: 98% - 99.9%

Forma y color: White To Off-White Powder

Peso molecular: 692.71

Ref: TM-T6512

Geneticin sulfate

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 692.71 g/mol

Ref: 3D-AG11347

G418 Disulfate

CAS: 108321-42-2, 49863-47-0

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Pureza: >90.0%(HPLC)(N)

Forma y color: White to Almost white powder to crystal

Peso molecular: 692.70

Ref: 3B-G0349

G-418 Sulphate (Geneticin) for tissue culture

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Forma y color: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow

Peso molecular: 692.70

Ref: SR-87858

G-418 Sulphate (Geneticin) extrapure

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Forma y color: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow

Peso molecular: 692.70

Ref: SR-58327

G-418.Sulfate, Sterile-Filtered Solution

CAS: 108321-42-2

M01802 - G-418.Sulfate, Sterile-Filtered Solution

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Pureza: >90.0%(HPLC)(N)

Forma y color: Liquid

Peso molecular: 692.7

Ref: 10-M01802

Geneticin Disulfate Salt

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Forma y color: White To Off-White

Peso molecular: 692.71

Ref: TR-G360580

Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

Fórmula: C₂₀H₄₄N₄O₁₈S₂

Pureza: Min. 97.0 Area-%

Peso molecular: 692.71 g/mol

Ref: 3D-G-2400

Geneticin Disulfate Salt

CAS: 108321-42-2

Fórmula: C₂₀H₄₀N₄O₁₀(H₂SO₄)

Peso molecular: 496.56 : 2(98.07)

Ref: ST-EA-CP-G33036