CAS 1092453-15-0

AZD-8529

CAS: 1092453-15-0

AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.

Fórmula: C₂₄H₂₄F₃N₅O₃

Forma y color: Solid

Peso molecular: 487.47

Ref: TM-T10432

AZD-8529

CAS: 1092453-15-0

AZD-8529 is a potentiating agent of metabotropic glutamate receptors. It is a mesylate prodrug that is converted to the active form, AZD-8529-mesylate, in vivo. The conversion is catalyzed by esterases and glucuronidases. AZD-8529 has been shown to be safe and well tolerated in patients with schizophrenia who were treated for 4 weeks with a daily dose of 600 mg or 900 mg. It also has a potentiating effect on metabotropic glutamate receptors, which may lead to increased signaling of these receptors in the brain. This may lead to improved cognition and mental health in patients with schizophrenia or other mental disorders.

Fórmula: C₂₄H₂₄F₃N₅O₃

Pureza: Min. 95%

Peso molecular: 487.5 g/mol

Ref: 3D-STB45315