CAS 1093412-18-0

Roflupram

CAS: 1093412-18-0

Roflupram, Selective PDE4 inhibitor (IC50=26.2 nM), oral/BBB permeable, reverses cognitive deficits, suppresses pro-inflammatory factors.

Fórmula: C₁₆H₂₀F₂O₄

Forma y color: Solid

Peso molecular: 314.32

Ref: TM-T24061

Roflupram

CAS: 1093412-18-0

Roflupram is a selective inhibitor of the enzyme response element binding protein (RBP), which is responsible for the activation of gene expression in the nucleus. It has been shown to inhibit the production of inflammatory mediators such as TNF-α, IL-1β, and IL-6. Roflupram also inhibits the production of amyloid protein by microglia cells, which may be related to its clinical relevance in treating Alzheimer's disease. Roflupram binds to RBP with high affinity and specificity, blocking its interaction with DNA and preventing gene expression. This drug may be used to treat autoimmune diseases or even cancer due to its ability to inhibit tumor growth.

Fórmula: C₁₆H₂₀F₂O₄

Pureza: Min. 95%

Peso molecular: 314.32 g/mol

Ref: 3D-TTB41218