CAS 1094-61-7

beta-nicotinamida mononucleótido

Descripción:

beta-nicotinamida mononucleótido (NMN) es un nucleótido derivado de ribosa, nicotinamida y fosfato. Juega un papel crucial en el metabolismo celular como precursor de dinucleótido de nicotinamida y adenina (NAD+), una coenzima vital involucrada en reacciones redox y producción de energía dentro de las células. NMN es reconocido por sus posibles beneficios para la salud, particularmente en la investigación sobre el envejecimiento, ya que puede ayudar a aumentar los niveles de NAD+, que tienden a disminuir con la edad. Este compuesto se encuentra típicamente en pequeñas cantidades en varios alimentos, incluyendo verduras y frutas. NMN es soluble en agua, lo que permite una fácil absorción en sistemas biológicos. Su estabilidad puede verse influenciada por factores como el pH y la temperatura, que son consideraciones importantes en el almacenamiento y la formulación. La investigación sobre NMN se ha expandido, centrándose en sus implicaciones para la salud metabólica, la neuroprotección y la longevidad en general. Sin embargo, aunque es prometedor, se necesitan más estudios para comprender completamente sus mecanismos y potencial terapéutico.

Fórmula: C₁₁H₁₅N₂O₈P

InChI: InChI=1/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1

Clave InChI: InChIKey=DAYLJWODMCOQEW-TURQNECASA-N

SMILES: O[C@H]1[C@@H](O[C@H](COP(=O)([O-])O)[C@H]1O)[N+]=2C=C(C(N)=O)C=CC2

Sinónimos:

• 3-(Aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium
• 3-Carbamoyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt
• 3-carbamoyl-1-(5-O-phosphonopentofuranosyl)pyridinium
• 3-carbamoyl-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridinium
• NMN
• NMN (mononucleotide)
• Nicotinamide mononucleotide
• Nicotinamide ribonucleoside 5′-phosphate
• Nicotinamide ribonucleotide
• Nicotinamide ribotide
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, hydroxide, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, inner salt
• Pyridinium, 3-carbamoyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt
• coenzyme NMN
• β-<span class="text-smallcaps">D</span>-NMN
• β-NMN
• β-Nicotinamide mononucleotide
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, hydroxide, inner salt
• 3-Carbamoyl-1-β-D-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt
• Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt
• β-Nicotinamide ononucleotide
• beta-D-NMN
• Nicotinamide nucleotide
• β-nicotinamide D-ribonucleotide
• NMN zwitterion
• β-Nicotinamide Moonucleotide
• Nicotimide mononucleotide
• 99% NMN CAS 1094 61 7
• β-Nicotinamide Mononucleotid
• Nicotinamide mononuclotide
• β-Nicotinamidse Mononucleotide
• β-D-NMN
• beta-Nicotinamide Moonucleotide
• NMN powder
• BETA-NMN POWDER

β-Nicotinamide mononucleotide

CAS: 1094-61-7

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: 97%

Forma y color: Solid

Peso molecular: 334.2192

Ref: IN-DA003880

β-Nicotinamide mononucleotide

CAS: 1094-61-7

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: ≥ 95.0%

Forma y color: White, off-white or pale yellow powder

Peso molecular: 334.22

Ref: 7W-GE9996

β-Nicotinamide Mononucleotide-13C6

CAS: 1094-61-7

Fórmula: C₅₁₃C₆H₁₅N₂O₈P

Peso molecular: 340.17

Ref: 4Z-N-133013

β-Nicotinamide mononucleotide

CAS: 1094-61-7

β-Nicotinamide mononucleotide

Pureza: ≥98%

Peso molecular: 334.22g/mol

Ref: 54-BUP15443

β-Nicotinamide Mononucleotide Sodium Salt

CAS: 1094-61-7

Fórmula: C₁₁H₁₄N₂O₈P·Na

Peso molecular: 333.21 22.99

Ref: 4Z-N-133014

Nicotinamide mononucleotide

CAS: 1094-61-7

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: 95%~99%

Peso molecular: 334.221

Ref: BP-BP4241

β-Nicotinamide Mononucleotide

CAS: 1094-61-7

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 334.22

Ref: 3B-N1123

β-Nicotinamide mononucleotide

CAS: 1094-61-7

β-nicotinamide mononucleotide (NMN) is a natural nucleotide and a key intermediate in the synthesis of coenzyme I (NAD+). Cost effective and quality assured.

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: 99.29% - >99.99%

Forma y color: Solid

Peso molecular: 334.22

Ref: TM-T4721

β-Nicotinamide Mononucleotide-d4

CAS: 1094-61-7

Fórmula: C₁₁H₁₁D₄N₂O₈P

Peso molecular: 338.25

Ref: 4Z-N-133006

β-Nicotinamide Mononucleotide-13C5

CAS: 1094-61-7

Fórmula: C₆₁₃C₅H₁₅N₂O₈P

Peso molecular: 339.18

Ref: 4Z-N-133007

b-Nicotinamide mononucleotide

CAS: 1094-61-7

b-Nicotinamide mononucleotide

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: By hplc: 99.5% by area (Typical Value in Batch COA)

Forma y color: white powder

Peso molecular: 334.21916g/mol

Ref: 54-BIB3016

β-Nicotinamide Mononucleotide

CAS: 1094-61-7

Stability Very Hygroscopic
Applications A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
References Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);

Fórmula: C₁₁H₁₅N₂O₈P

Forma y color: White

Peso molecular: 334.22

Ref: TR-N407765

β-Nicotinamide-d4 Mononucleotide (d4-major)

Producto controlado

CAS: 1094-61-7

Fórmula: C₁₁D₄H₁₁N₂O₈P

Forma y color: White To Off-White

Peso molecular: 338.244

Ref: TR-N407768

b-Nicotinamide mononucleotide

CAS: 1094-61-7

b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: Min. 95 Area-%

Forma y color: Powder

Peso molecular: 334.22 g/mol

Ref: 3D-NN45555

ß-Nicotinamide Mononucleotide (ß-NMN) extrapure, 98%

CAS: 1094-61-7

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: min. 98.0%

Forma y color: White, Crystalline powder

Peso molecular: 334.22

Ref: SR-95130

ß-Nicotinamide Mononucleotide (ß-NMN) for cell culture, 99%, Endotoxin (BET) 0.05EU/mg

CAS: 1094-61-7

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: min. 99.0%

Forma y color: White, Crystalline powder.

Peso molecular: 334.22

Ref: SR-63509

((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate

CAS: 1094-61-7

Fórmula: C₁₁H₁₅N₂O₈P

Pureza: 95%

Forma y color: Solid

Peso molecular: 334.221

Ref: 10-F455506

β-Nicotinamide Mononucleotide-13C5

Producto controlado

CAS: 1094-61-7

Applications The labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
References Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);

Fórmula: C₅C₆H₁₅N₂O₈P

Forma y color: Neat

Peso molecular: 339.182

Ref: TR-N407767