CAS 109806-71-5

2-[4-[(4-clorofenil)-fenilmetil]piperazin-1-il]etanol

Descripción:

2-[4-[(4-clorofenil)-fenilmetil]piperazin-1-il]etanol, con el número CAS 109806-71-5, es un compuesto químico que pertenece a la clase de derivados de piperazina. Esta sustancia presenta un anillo de piperazina, que es un anillo de seis miembros que contiene dos átomos de nitrógeno, y está sustituido con un grupo fenilmetilo y un grupo 4-clorofenilo. La presencia del grupo hidroxilo (-OH) en la parte de etanol de la molécula contribuye a su posible solubilidad en disolventes polares. Este compuesto se estudia a menudo por sus propiedades farmacológicas, particularmente en el contexto de la neurofarmacología, ya que se sabe que los derivados de piperazina exhiben diversas actividades biológicas, incluidos efectos antipsicóticos y ansiolíticos. La sustitución clorofenílica puede influir en su interacción con objetivos biológicos, potencialmente mejorando su eficacia o alterando su perfil farmacocinético. En general, las características estructurales de este compuesto sugieren que puede tener implicaciones significativas en la química medicinal y el desarrollo de fármacos.

Fórmula: C₁₉H₂₅Cl₃N₂O

InChI: InChI=1S/C19H23ClN2O/c20-18-8-6-17(7-9-18)19(16-4-2-1-3-5-16)22-12-10-21(11-13-22)14-15-23/h1-9,19,23H,10-15H2

Clave InChI: InChIKey=ZJQSBXXYLQGZBR-UHFFFAOYSA-N

SMILES: C(N1CCN(CCO)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3

Sinónimos:

• 1-Piperazineethanol, 4-(p-chloro-α-phenylbenzyl)-
• 1-Piperazineethanol, 4-[(4-chlorophenyl)phenylmethyl]-
• 2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol
• 2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-piperazin-1-YL}-ETHANOL
• 2-{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethanol
• 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazine
• 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol
• Cetirizine ethanol
• Cetirizine impurity G
• Unii-Pgv947X9B1
• 2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethanol
• Cetirizine Impurity 15 Monomer （Cetirizine EP Impurity G Monomer ）
• 4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone
• 2-[4-{Chlorophenyl}Phenylmethyl]-1-
• Levocetirizine Impurity G
• 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
• Cetirizine -EP-Imp-G
• Levocetirizine Impurity 6
• Cetirizine EP Impurity G Hydrochloride

Cetirizine EP Impurity G (Cetirizine USP Related Compound G (Free Form), Levocetirizine EP Impurity H)

CAS: 109806-71-5

Fórmula: C₁₉H₂₃ClN₂O

Forma y color: Pale Yellow Semi-Solid (Low M P )

Peso molecular: 330.86

Ref: 4Z-C-2012

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol

CAS: 109806-71-5

Stability Very Hygroscopic
Applications 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.
References Rezaei, Z. et al.: Archiv. Pharm., 344, 658 (2011)

Fórmula: C₁₉H₂₃ClN₂O

Forma y color: White To Off-White

Peso molecular: 330.85

Ref: TR-C377565

2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHANOL

CAS: 109806-71-5

Fórmula: C₁₉H₂₅Cl₃N₂O

Pureza: 95.0%

Peso molecular: 403.77

Ref: 10-F540017

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol-d4

Producto controlado

CAS: 109806-71-5

Fórmula: C₁₉H₁₉D₄ClN₂O

Forma y color: Neat

Peso molecular: 334.88

Ref: TR-C377567

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride

CAS: 109806-71-5

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride is a cholinergic drug that is used to treat allergic rhinitis in children and adults. It has been shown to be well tolerated in pediatric patients and geriatric patients, as well as being an innovative, labile, and biopharmaceutical compound. 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride is not metabolized by the liver and does not have significant side effects. It has a low potential for abuse because of its low solubility in water. It is an antihistamine that blocks the action of histamine at H1 receptors on smooth muscle cells in the nose, which helps reduce nasal congestion and sneezing.

Fórmula: C₁₉H₂₃ClN₂O·2HCl

Pureza: Min. 95%

Peso molecular: 403.77 g/mol

Ref: 3D-FC53582