CAS 1105067-88-6
:Ácido 1H-pirrol-1-heptanoico, 2-(4-fluorofenil)-β,δ-dihidroxi-5-(1-metiletil)-3-fenil-4-[(fenilamino)carbonil]-, sal de calcio (2:1), (βS,δS)-
Descripción:
Ácido 1H-pirrol-1-heptanoico, 2-(4-fluorofenil)-β,δ-dihidroxi-5-(1-metiletil)-3-fenil-4-[(fenilamino)carbonil]-, sal de calcio (2:1), (βS,δS)- es un compuesto orgánico complejo caracterizado por sus características estructurales únicas, que incluyen un anillo de pirrol y múltiples grupos funcionales como hidroxilo, carbonilo y moieties aromáticos. La presencia de una sal de calcio indica que forma un complejo de coordinación, lo que puede mejorar su estabilidad y solubilidad en sistemas biológicos. El grupo fluorofenilo sugiere aplicaciones potenciales en química medicinal, ya que los compuestos fluorados a menudo exhiben farmacocinéticas alteradas y una mayor estabilidad metabólica. La estereoquímica del compuesto, denotada por la configuración (βS,δS), implica disposiciones espaciales específicas que pueden influir en su actividad biológica e interacciones con receptores o enzimas. En general, esta sustancia puede poseer propiedades interesantes para la investigación en productos farmacéuticos o agroquímicos, aunque serían necesarios estudios detallados para elucidar sus efectos biológicos específicos y aplicaciones potenciales.
Fórmula:C33H35FN2O5Ca
InChI:InChI=1S/C33H35FN2O5.Ca/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/t26-,27-;/m0./s1
Clave InChI:InChIKey=BWFCZHDTTAYGNN-WMXJXTQLSA-N
SMILES:C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@@H](C[C@@H](CC(O)=O)O)O)C2C(C)C)C3=CC=C(F)C=C3)C4=CC=CC=C4.[Ca]
Sinónimos:- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (βS,δS)-
- -7-(2-(4-fluorophenyl)
- Atorvastatin Related Compound E (10 mg) (3S, 5S enantiomer of Atorvastatin Calcium)
- Atorvastatin impurity 6/Atorvastatin EP Impurity E Calcium Salt/(3S,5S)-Atorvastatin Calcium Salt/((3S,5S)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- (phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate) Calcium Salt
- "Atorvastatin corresponds to isomer Atorvastatin calcium 2020 Pharmacopoeia Impurity VIII)"
- (betaS,deltaS)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid calcium salt (2:1)
- (βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemicalcium salt
- 3S,5S enantiomer-Atorvastatin calcium
- -5-isopropyl-3-phenyl-4-(phenylcarbamoyl)
- 3S, 5S enantioMer of Atorvastatin CalciuM
- Atorvastatin Impurity E calcium salt
- (βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt
- Calcium (3S,5S)
- (phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate)
- USP Impurity E
- Atorvastatin imp E
- calcium(II)
- Atorvastatin impurity E
- -3,5-dihydroxyheptanoate
- Atorvastatin Impurity E(USP)
- Atorvastatin Enantiomer
- Atorvastatin Related CoMpound E
- USP Atorvastatin Related Compound E
- (3S,5S)-Atorvastatin hemicalcium salt
- Atorvastatin EP IMP E
- Atorvastatin calcium-3
- monocalcium mono((3S,5S)-
- Atorvastatin Impurity 79 Calcium Salt
- Atorvastatin EP Impurity E (Ca Salt)
- Atorvastatin calcium VIII
- -1H-pyrrol-1-yl)
- ent-Atorvastatin Calcium
- calcium:(3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
- Atorvastatin USP RC E
- ((3S,5S)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-
- ent-Atorvastatin
- (3S,5S)-Atorvastatin Calcium Salt
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Encontrado 6 productos.
Atorvastatin Related Compound E (Calcium(3S,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2))
CAS:Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoiFórmula:C66H68CaF2N4O10Forma y color:White PowderPeso molecular:1154.45294Calcium (3S,5S)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
CAS:Fórmula:C66H68CaF2N4O10Forma y color:SolidPeso molecular:1155.3417(3S,5S)-Atorvastatin Calcium Salt
CAS:Producto controlado<p>Impurity Atorvastatin Related Compound E<br>Applications Impuritiy of Atorvaststin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Atorvastatin Related Compound E<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),<br></p>Fórmula:C33H34FN2O5·CaForma y color:NeatPeso molecular:1155.34(betaS,deltaS)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole- 1-heptanoic acid calcium salt (2:1)
CAS:<p>(betaS,deltaS)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole- 1-heptanoic acid calcium salt (2:1) is a fluorinated derivative of the natural metabolite 2-(4-fluorophenyl)-beta,delta-dihydroxy -5-(1 methylethyl)-3 phenyl 4-[(phenylamino)carbonyl]-1H pyrrole 1 heptanoic acid. It is an enantiomer of the racemate with optical purity > 98%. The compound has been used as a pharmacological and supramolecular chemistry probe for assays and chemosensors.</p>Fórmula:C66H68CaF2N4O10Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:1,155.34 g/mol
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