CAS 111011-76-8

2-(bencil-fenil-amino)etil 5-(5,5-dimetil-2-oxo-1,3-dioxa-2$l^{5}-fosfaciclohex-2-il)-2,6-dimetil-4-(3-nitrofenil)-1,4-dihidropiridina-3-carboxilato

Descripción:

La sustancia química conocida como "2-(bencil-fenil-amino)etil 5-(5,5-dimetil-2-oxo-1,3-dioxa-2$l^{5}-fosfaciclohex-2-il)-2,6-dimetil-4-(3-nitrofenil)-1,4-dihidropiridina-3-carboxilato," con el número CAS 111011-76-8, es un compuesto orgánico complejo que presenta múltiples grupos funcionales, incluyendo un grupo amino, un carboxilato y un moiety nitrofenilo. Su estructura sugiere aplicaciones potenciales en química medicinal, particularmente en el desarrollo de fármacos debido a la presencia del núcleo de dihidropiridina, que a menudo se asocia con bloqueadores de canales de calcio. El componente fosfaciclohexano puede conferir propiedades únicas, como una mayor estabilidad o bioactividad. La presencia del grupo nitro indica potencial para una mayor reactividad o interacción con objetivos biológicos. En general, este compuesto ejemplifica el diseño intrincado que a menudo se encuentra en el desarrollo de medicamentos, donde varios sustituyentes se incorporan estratégicamente para optimizar la eficacia y selectividad. Se necesitarían más estudios para elucidar sus actividades biológicas específicas y aplicaciones terapéuticas potenciales.

Fórmula: C₃₆H₄₅ClN₃O₈P

InChI: InChI=1/C34H38N3O7P.C2H6O.ClH/c1-24-30(33(38)42-19-18-36(28-15-9-6-10-16-28)21-26-12-7-5-8-13-26)31(27-14-11-17-29(20-27)37(39)40)32(25(2)35-24)45(41)43-22-34(3,4)23-44-45;1-2-3;/h5-17,20,31,35H,18-19,21-23H2,1-4H3;3H,2H2,1H3;1H

SMILES: CC1=C(C(c2cccc(c2)N(=O)=O)C(=C(C)N1)P1(=O)OCC(C)(C)CO1)C(=O)OCCN(Cc1ccccc1)c1ccccc1.CCO.Cl

Sinónimos:

• Hydrochloride
• Efonidipine hydrochloride ethanolate
• Efonidipine hydrochloride ethanol
• Efonidipine HCl ethanolate
• Ethanol, compd. with 2-(phenyl(phenylmethyl)amino)ethyl 5-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate P-oxide monohydrochloride (1:1)
• Ethanol, compd. with 2-(phenyl(phenylmethyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate monohydrochloride
• NZ 105 ethanolate
• Unii-3Br983K69O
• 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yl)-4-(3-nitrophenyl)-, 2-(phenyl(phenylmethyl)amino)ethyl ester, P-oxide, monohydrochloride
• 3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(phenyl(phenylmethyl)amino)ethyl ester, monohydrochloride, compd. with ethanol (1
• 1)
• 2-[Benzyl(Phenyl)Amino]Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate

2-(benzyl(phenyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate compound with ethanol (1:1) hydrochloride

CAS: 111011-76-8

Fórmula: C₃₆H₄₅ClN₃O₈P

Pureza: 98%

Forma y color: Solid

Peso molecular: 714.1846

Ref: IN-DA0082Z5

2-(Benzyl(Phenyl)Amino)Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate Ethanol Hydrochloride

CAS: 111011-76-8

2-(Benzyl(Phenyl)Amino)Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate Ethanol Hydrochloride

Pureza: 98%

Peso molecular: 714.18g/mol

Ref: 54-OR1027315

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine hydrochloride monoethanolate

Pureza: ≥98%

Peso molecular: 714.18g/mol

Ref: 54-BUP06729

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.

Fórmula: C₃₆H₄₅ClN₃O₈P

Pureza: >99.99%

Forma y color: Solid

Peso molecular: 714.18

Ref: TM-T8401

Efonidipine Hydrochloride Monoethanolate

Producto controlado

CAS: 111011-76-8

Fórmula: C₃₄H₃₈N₃O₇P·C₂H₆O·ClH

Forma y color: Neat

Peso molecular: 714.185

Ref: TR-E436005

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine hydrochloride monoethanolate is a calcium channel blocker that blocks voltage-dependent calcium channels. It has been shown to reduce the incidence of bowel disease in humans, and is used to treat high blood pressure and heart failure. Efonidipine hydrochloride monoethanolate can be administered orally, intravenously, or by injection. The drug has been shown to have an effect on the concentration–time curve of maternal blood glucose levels in pregnant women with diabetes mellitus type 1. Efonidipine hydrochloride monoethanolate also may cause drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. It will bind to matrix proteins in atherosclerotic lesions and inhibit light-induced fluorescence. This drug can be used as an analytical tool for measuring concentrations of various substances in the body fluids of patients with metabolic disorders such as diabetes mellitus type 1 or 2, hyperlipidaemia, hypertension

Fórmula: C₃₆H₄₅ClN₃O₈P

Pureza: Min. 95%

Peso molecular: 714.18 g/mol

Ref: 3D-BE179488