CAS 111119-28-9

glicina-arginina-glicina-ácido aspártico-serina-prolina-lisina

Descripción:

La sustancia química conocida como "glicina-arginina-glicina-ácido aspártico-serina-prolina-lisina" es un péptido compuesto por seis aminoácidos: glicina (Gly), arginina (Arg), ácido aspártico (Asp), serina (Ser), prolina (Pro) y lisina (Lys). Este péptido se estudia a menudo por su actividad biológica y sus posibles aplicaciones en campos como la bioquímica y la farmacología. Su secuencia sugiere que puede desempeñar un papel en la señalización celular, particularmente en interacciones con moléculas de adhesión celular y receptores. La presencia de aminoácidos cargados positivamente como la arginina y la lisina puede contribuir a su capacidad para interactuar con componentes celulares cargados negativamente. Además, la estructura del péptido puede influir en su solubilidad, estabilidad y función biológica general. El número CAS 111119-28-9 identifica de manera única este péptido específico, facilitando su reconocimiento en la literatura científica y bases de datos. En general, glicina-arginina-glicina-ácido aspártico-serina-prolina-lisina ejemplifica la complejidad de las interacciones de péptidos en sistemas biológicos y destaca la importancia de las secuencias de aminoácidos en la determinación de la función.

Fórmula: C₂₈H₄₉N₁₁O₁₁

InChI: InChI=1/C28H49N11O11/c29-8-2-1-5-16(27(49)50)37-25(47)19-7-4-10-39(19)26(48)18(14-40)38-24(46)17(11-22(43)44)36-21(42)13-34-23(45)15(35-20(41)12-30)6-3-9-33-28(31)32/h15-19,40H,1-14,29-30H2,(H,34,45)(H,35,41)(H,36,42)(H,37,47)(H,38,46)(H,43,44)(H,49,50)(H4,31,32,33)/t15-,16-,17-,18-,19-/m0/s1

SMILES: C(CCN)C[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)[C@H](CO)N=C([C@H](CC(=O)O)N=C(CN=C([C@H](CCCNC(=N)N)N=C(CN)O)O)O)O)O

Sinónimos:

• H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH
• glycyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-alpha-aspartyl-L-seryl-L-prolyl-L-lysine
• GRGDSPK
• GLY-ARG-GLY-ASP-SER-PRO-LYS
• EMD 56574
• Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC)
• L-Lysine, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-
• GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE
• GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE
• glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH

CAS: 111119-28-9

GRGDSPK, fibronectin analog.

Fórmula: C₂₈H₄₉N₁₁O₁₁

Pureza: 98.6%

Peso molecular: 715.77

Ref: 01-4102088

Gly-Arg-Gly-Asp-Ser-Pro-Lys

CAS: 111119-28-9

Fórmula: C₂₈H₄₉N₁₁O₁₁

Peso molecular: 715.76

Ref: 7W-GK2645

GRGDSPK

CAS: 111119-28-9

GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.

Fórmula: C₂₈H₄₉N₁₁O₁₁

Pureza: 98%

Forma y color: Solid

Peso molecular: 715.76

Ref: TM-T7566

RGD Peptide GRGDSPK

CAS: 111119-28-9

GRGDSPK is the sequence found in cell binding region of fibronectin and many other proteins. The sequence, referred to as RGD, is critical for facilitating cell adhesion.-RGD peptide is an adhesive peptide which can be used in a biomaterial context to attach cells to a range of materials. RGD has many applications including as an antigen for integrin adhesion of thymocytes to thymic epithelial cells. RGD can be used as a blocking peptide to study bacteria and fibronectin. RGD can also be used on collagen-coated plates for study of integrins' role in progenitor cell differentiation. Delivery of RGD peptide inhibits bone mineralization in a dose-dependent manner so GRGDSPK is used to study the role of integrins in bone formation. The presence of RGD peptide dramatically alters bone morphology, with a disruption of osteoblast and mineralized matrix organisation. RGD is a vital research tool in bone formation and integrin.

Fórmula: C₂₈H₄₉N₁₁O₁₁

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 715.4 g/mol

Ref: 3D-CRB1000549

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH

CAS: 111119-28-9

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH is a peptide that has been shown to have chemotactic activity for monocytes and polymorphonuclear leucocytes, which are cells that participate in the inflammatory response. It also has biological properties that are reactive with hydroxyl groups and can be used to generate monoclonal antibodies. H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH has been shown to stimulate the migration of galleria mellonella larvae, suggesting it may have potential as an antiinflammatory agent.

Fórmula: C₂₈H₄₉N₁₁O₁₁

Pureza: Min. 95%

Peso molecular: 715.76 g/mol

Ref: 3D-FG109749

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH

CAS: 111119-28-9

GRGDSPK, fibronectin analog.

Fórmula: C₂₈H₄₉N₁₁O₁₁

Pureza: 98.7%

Peso molecular: 715.77

Ref: 01-4011392