CAS 112108-01-7

(-)-(6aS,13bR)-11-Cloro-12-hidroxi-7-metil-6,6a,7,8,9,13b-hexahidro-5H-benzo[d]nafto[2,1-d]azepina

Descripción:

La sustancia química conocida como "(-)-(6aS,13bR)-11-Cloro-12-hidroxi-7-metil-6,6a,7,8,9,13b-hexahidro-5H-benzo[d]nafto[2,1-d]azepina" con el número CAS 112108-01-7 es un compuesto orgánico complejo caracterizado por su estructura bicíclica única, que incluye un marco de benzo[d]nafto[2,1-d]azepina. Este compuesto presenta varios grupos funcionales, incluyendo un átomo de cloro y un grupo hidroxilo, que contribuyen a su reactividad química y potencial actividad biológica. La estereoquímica indicada por la configuración específica en las posiciones 6a y 13b sugiere que puede exhibir propiedades quirales, influyendo en sus interacciones en sistemas biológicos. Tales compuestos son a menudo de interés en la química medicinal debido a sus posibles efectos farmacológicos. La presencia de múltiples anillos y sustituyentes también puede afectar su solubilidad, estabilidad y comportamiento general en diversos entornos químicos. Se necesitarían más estudios para elucidar sus aplicaciones específicas y mecanismos de acción.

Fórmula: C₁₉H₂₁Cl₂NO

InChI: InChI=1/C19H20ClNO.ClH/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21;/h2-5,10-11,17,19,22H,6-9H2,1H3;1H/t17-,19+;/m0./s1

Clave InChI: InChIKey=DMJWENQHWZZWDF-PKOBYXMFSA-N

SMILES: CN1[C@@]2([C@@](C=3C(=CC(Cl)=C(O)C3)CC1)(C=4C(CC2)=CC=CC4)[H])[H]

Sinónimos:

• (6aS,13bR)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol
• (6aS,13bR)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol
• (6aS,13bR)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol hydrochloride (1:1)
• 5H-Benzo[d]naphth[2,1-b]azepin-12-ol, 11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-, (6aS,13bR)-
• 5H-Benzo[d]naphth[2,1-b]azepin-12-ol, 11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-, (6aS-trans)-
• Ecopipam
• Psyrx 101
• Sch-39166
• ECOPIPAM(6 AS,13 BR)-FORM
• (6aβ,13bα)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol
• Unii-0X748o646k
• Ecopipam [inn]
• 6,7,7A,8,9,13B-Hexahydro-3-chloro-2-hydroxy-N-methyl-5H-benzo(D)naphtho(2,1B)azepine
• Ecopipam-d4
• (-)-(6aS,13bR)-11-Chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-d]azepine
• (6aS)-11-Chloro-6,6aβ,7,8,9,13bα-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol
• [13C6]-Ecopipam

Ecopipam

CAS: 112108-01-7

Ecopipam

Pureza: ≥98%

Peso molecular: 313.82g/mol

Ref: 54-BUP11564

Ecopipam

CAS: 112108-01-7

Fórmula: C₁₉H₂₀ClNO

Peso molecular: 313.82

Ref: 7W-GP0063

Ecopipam

CAS: 112108-01-7

Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.

Fórmula: C₁₉H₂₀ClNO

Pureza: 99.68%

Forma y color: Solid

Peso molecular: 313.82

Ref: TM-T31602

Ecopipam

CAS: 112108-01-7

Ecopipam is an antagonist drug that blocks the 5-HT2A receptor. It has been shown to have a high affinity for this receptor, and it is one of the most potent antagonists in its class. Ecopipam has been shown to cause a reduction in locomotor activity in rats when administered at low doses and to inhibit brain functions such as dopamine release, although these effects are not observed at higher doses. This drug also has side-effects such as drowsiness and sedation, which may be due to its effect on brain function. Ecopipam does not seem to have any significant interactions with other drugs, and is therefore safe for use in combination with other drugs.

Fórmula: C₁₉H₂₀ClNO

Pureza: Min. 95%

Peso molecular: 313.82 g/mol

Ref: 3D-FE159526