CAS 113-52-0

Clorhidrato de imipramina

Descripción:

La clorhidrato de imipramina es un antidepresivo tricíclico que se utiliza principalmente en el tratamiento del trastorno depresivo mayor y ciertos trastornos de ansiedad. Funciona inhibiendo la recaptación de neurotransmisores, particularmente norepinefrina y serotonina, aumentando así su disponibilidad en la hendidura sináptica. Este mecanismo contribuye a sus efectos antidepresivos. La sustancia aparece como un polvo cristalino blanco a blanco amarillento y es soluble en agua, lo que facilita su administración en entornos clínicos. La clorhidrato de imipramina tiene una vida media relativamente larga, lo que permite una dosificación una vez al día en muchos casos. Los efectos secundarios comunes pueden incluir boca seca, sedación, aumento de peso y posibles efectos cardiovasculares, lo que requiere un monitoreo cuidadoso, especialmente en pacientes con condiciones preexistentes. Debido a su perfil farmacológico, se clasifica como un medicamento de prescripción y debe usarse bajo supervisión médica. Además, es importante considerar las posibles interacciones con otros medicamentos, así como el riesgo de síntomas de abstinencia al interrumpirlo. En general, la clorhidrato de imipramina sigue siendo una opción significativa en la farmacoterapia de la depresión y trastornos relacionados.

Fórmula: C₁₉H₂₅ClN₂

InChI: InChI=1/C20H25N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-11,20H,7,12-15H2,1-2H3;1H

Clave InChI: InChIKey=XZZXIYZZBJDEEP-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Sinónimos:

• 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N-dimethylpropan-1-aminium chloride
• 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
• 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepin hydrochloride
• 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
• 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride
• Apo-Imipramine
• Censtim
• Censtin
• Chrytemin
• Deprinol
• Depsol
• Dimipressin
• Dipd
• Dyna-Zina
• Efuranol
• Eupramin
• Feinalmin
• G 22355
• Imavate
• Imidobenzyle
• Imidol
• Imilanyle
• Imipramina, Clorhidrato
• Imipramine hydrochloride
• Imipramine monohydrochloride
• Imipramine, chlorhydrate
• Imipraminhydrochlorid
• Imiprin
• Imizin
• Imizine
• Imizinum
• Impril
• Intalpram
• Iramil
• Irmin
• Janimine
• Melipramin
• Melipramine hydrochloride
• N-(3-Dimethylaminopropyl)iminodibenzyl hydrochloride
• N-(γ-Dimethylaminopropyl)iminodibenzyl hydrochloride
• Novo-pramine
• Praminil
• Presamine
• Promiben
• Pryleugan
• SK-Pramine
• Surplix
• Teperine
• Timolet
• Tipramine
• Tofranil
• Tofranile
• cocapimipramine25
• f)azepine,10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz(hydrochlor
• chimoreptin
• f)azepine-5-propanamine,10,11-dihydro-n,n-dimethyl-5h-dibenz(monohydroch
• 10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• f)azepine,5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(monohydrochloride
• IMIPRAMINE HCL
• f)azepine,5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(monohydrochl
• LABOTEST-BB LT00452014
• 10,11-Dihydro-N,N-dimithyl-5,H-dibenz[b,f]azepine-5-propanamine
• 5-(3-dimethylaminopropyl)-10,11-dihydro-5h-dibenz(b,f)azepinehydrochloride
• 10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz[b,f]azepine hydrochloride
• 10,11-DIHYDRO-N,N-DIMETHYL-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• antideprinhydrochloride

Imipramine Hydrochloride

CAS: 113-52-0

Applications Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters. Has little effect on the dopamine transporter.
References Wood, M.D., et al.: Neuropharmacology, 26, 1081 (1987), Casis, O., et al.: J. Cardiovasc. Pharmacol., 32, 521 (1998), Linner, L., et al.: Biol. Psychiatry, 46, 766 (1999), Teschemacher, et al.: Br. J. Pharmacol., 128, 479 (1999),

Fórmula: C₁₉H₂₄N₂·ClH

Forma y color: Off White

Peso molecular: 316.87

Ref: TR-I465980

Clomipramine EP Impurity B

CAS: 113-52-0

Fórmula: C₁₉H₂₄N₂HCl

Peso molecular: 280.4 : 36.5

Ref: ST-EA-CP-C30002

Imipramine HCl - Bio-X ™

Producto controlado

CAS: 113-52-0

Imipramine is a drug that belongs to the class of tricyclic antidepressant drugs. It is used in the treatment of depression and childhood enuresis. It is a potent inhibitor of serotonin and norepinephrine reuptake. Imipramine blocks D-2 receptors, H1 receptors, α-1 and α-2 adrenergic receptors and muscarinic receptors. Also, it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.

Fórmula: C₁₉H₂₄N₂•HCl

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 316.87 g/mol

Ref: 3D-BI164574

Imipramine hydrochloride

Producto controlado

CAS: 113-52-0

Imipramine hydrochloride is a hydrochloride salt form of imipramine, a surface active tricyclic drug, a potent inhibitor of serotonin and norepinephrine reuptake. It has a greater affinity for the serotonin and it has more anticholinergic side effects which can be helpful in treating enuresis. Imipramine blocks D-2 receptors, H1 receptors, alpha 1 and alpha 2 adrenergic receptors and muscarinic receptors. It is used for therapy of depression (major and bipolar) and nocturnal enuresis in children. Also it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.

Fórmula: C₁₉H₂₅ClN₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 316.87 g/mol

Ref: 3D-FI24561