CAS 113-80-4

argiprestocina

Descripción:

argiprestocina, con el número CAS 113-80-4, es un péptido sintético que actúa como vasodilatador y se utiliza principalmente en entornos de investigación. Se conoce por su capacidad para imitar la acción de ciertos péptidos endógenos, influyendo en la relajación del músculo liso vascular y potencialmente impactando la dinámica del flujo sanguíneo. La sustancia se caracteriza por su secuencia específica de aminoácidos, que contribuye a su actividad biológica. argiprestocina se estudia a menudo por sus efectos en la función cardiovascular y sus posibles aplicaciones terapéuticas en condiciones relacionadas con la salud vascular. Como péptido, es típicamente soluble en soluciones acuosas y puede requerir un manejo cuidadoso para mantener su estabilidad. Su perfil farmacológico incluye interacciones con receptores específicos, lo que lleva a varias respuestas fisiológicas. Sin embargo, la información detallada sobre su seguridad, eficacia y aplicaciones clínicas es limitada, ya que se utiliza principalmente en contextos experimentales en lugar de un uso clínico generalizado.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

InChI: InChI=1/C43H67N15O12S2/c1-3-21(2)34-41(69)53-26(12-13-31(45)60)37(65)55-28(17-32(46)61)38(66)56-29(20-72-71-19-24(44)35(63)54-27(39(67)57-34)16-22-8-10-23(59)11-9-22)42(70)58-15-5-7-30(58)40(68)52-25(6-4-14-50-43(48)49)36(64)51-18-33(47)62/h8-11,21,24-30,34,59H,3-7,12-20,44H2,1-2H3,(H2,45,60)(H2,46,61)(H2,47,62)(H,51,64)(H,52,68)(H,53,69)(H,54,63)(H,55,65)(H,56,66)(H,57,67)(H4,48,49,50)/t21-,24-,25-,26-,27-,28-,29-,30-,34-/m0/s1

SMILES: CC[C@H](C)[C@H]1C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(=N)O)C(=N[C@@H](CSSC[C@@H](C(=N[C@@H](Cc2ccc(cc2)O)C(=N1)O)O)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCNC(=N)N)C(=NCC(=N)O)O)O)O)O)O

Sinónimos:

• Argiprestocin [INN]
• (Arg(sup 8))oxytocin
• 8-Arg-vasotocin
• 8-Arginine vasotocin
• 8-L-Arginineoxytocin
• Arg-vasotocin
• Arginine vasotocin
• Argiprestocina
• Argiprestocina [INN-Spanish]
• Argiprestocine
• Argiprestocine [INN-French]
• Argiprestocinum
• Argiprestocinum [INN-Latin]
• Brn 4902334
• Natriuretic hormone (ox pineal)
• Unii-W6S6Ury8Of
• 8-Arginineoxytocin
• Oxytocin, 8-L-arginine-
• 1-{[(4R,7S,10S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}prolyl-N~5~-(diaminomethylidene)-L-ornithylglycinamide
• 1-{[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-N~5~-(diaminomethylidene)-L-ornithylglycinamide
• Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-Nh2
• Argiprestocin
• 8-l-arginine-oxytoci
• [ARG8]-VASOTOCIN
• H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2, (Disulfide bond)
• CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 USP/EP/BP
• H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2, CYS1,6, CYCLIC
• CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2(DISULFIDE BRIDGE:CYS1-CYS6)
• 8-argininevasotocin
• 1-[(1R,4S,7S,13S,16R)-16-amino-4-(2-amino-2-oxoethyl)-7-(3-amino-3-oxopropyl)-10-[(2S)-butan-2-yl]-13-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
• 1-[[(1R,4S,7S,13S,16R)-16-azanyl-4-(2-azanyl-2-oxo-ethyl)-7-(3-azanyl-3-oxo-propyl)-10-[(2S)-butan-2-yl]-13-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-18,19-dithia-2,5,8,11,14-pentazacycloicos-1-yl]carbonyl]-N-[(2S)-1-[(2-azanyl-2-oxo-ethyl)amino]-5-[bis(azanyl)methylideneamino]-1-oxo-pentan-2-yl]pyrrolidine-2-carboxamide
• 1-[(1R,4S,7S,13S,16R)-16-amino-4-(2-amino-2-keto-ethyl)-7-(3-amino-3-keto-propyl)-13-(4-hydroxybenzyl)-3,6,9,12,15-pentaketo-10-[(1S)-1-methylpropyl]-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]-N-[(1S)-1-[(2-amino-2-keto-ethyl)carbamoyl]-4-guanidino-butyl]pyrrolidine-2-carboxamide
• [ARG8]-VASOTOCIN (FROG, CHICKEN)
• VASOTOCIN ARG 8
• (arg(sup8))oxytocin
• [Arg8]-Vasotocin trifluoroacetate
• H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Cys1-Cys6)
• VASOTOCIN, [ASU16,ARG8]
• CYIQNCPRG-NH2
• H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2

(Arg⁸)-Vasotocin (Salt form acetate)

CAS: 113-80-4

Non-mammalian Arg-vasopressin/oxytocin analog.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

Pureza: 98.7%

Forma y color: White Whitish Powder

Peso molecular: 1050.23

Ref: 01-4100576

(Arg⁸)-Vasotocin (Salt form trifluoroacetate)

CAS: 113-80-4

Vasotocin (AVT, argiprestocin) is the vasopressin/oxytocin analog produced in birds, amphibians and fish. AVT shows antidiuretic as well as reproductive activities.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

Pureza: 98.0%

Forma y color: White

Peso molecular: 1050.23

Ref: 01-4031338

[Arg8]-Vasotocin

CAS: 113-80-4

[Arg8]-Vasotocin is a hormone present in the neurohypophysis of nonmammalian vertebrates that is related to vasopressin and oxytocin.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 1050.22

Ref: TM-TP1400

[Arg8]-Vasotocin trifluoroacetate

CAS: 113-80-4

Vasotocin is a peptide hormone that regulates a variety of physiological processes, including blood pressure, water permeability, and locomotor activity. Vasotocin is synthesized from the precursor arginine vasotocin (AVT) by the enzyme polypeptide chain elongation. AVT can bind to two different receptors: one that is inhibitory and one that is excitatory. The inhibitory receptor for AVT can be activated by vasopressin or oxytocin, while the excitatory receptor for AVT can be activated by atrial natriuretic peptide. Activation of both receptors leads to increased blood flow and decreased blood pressure. Vasotocin has been shown to have an inhibitory effect on the polymerase chain reaction in human serum and to have a model system in rats.

Fórmula: C₄₃H₆₇N₁₅O₁₂S₂

Pureza: Min. 95%

Peso molecular: 1,050.22 g/mol

Ref: 3D-FA73663