CAS 113866-14-1

BOC-GRR-AMC

Descripción:

BOC-GRR-AMC, con el número CAS 113866-14-1, es un compuesto químico que sirve como sustrato en ensayos bioquímicos, particularmente en el estudio de las proteasas. Se caracteriza por la presencia de un grupo protector BOC (tert-butiloxicarbonilo), que se utiliza comúnmente en la síntesis de péptidos para proteger los grupos amino. La secuencia GRR indica la presencia de aminoácidos específicos, probablemente arginina y glicina, que pueden ser relevantes para la especificidad enzimática. El grupo AMC (7-amino-4-metilcumarina) es un grupo fluorogénico que emite fluorescencia al ser escindido, lo que lo hace útil para monitorear la actividad enzimática en tiempo real. Este compuesto se utiliza típicamente en entornos de investigación para investigar la actividad proteolítica y la cinética enzimática. Su estabilidad, solubilidad en disolventes orgánicos y la capacidad de proporcionar una señal fluorescente medible al reaccionar lo convierten en una herramienta valiosa en la investigación bioquímica y farmacéutica. Las condiciones adecuadas de manejo y almacenamiento son esenciales para mantener su integridad y reactividad.

Fórmula: C₂₉H₄₄N₁₀O₇

Sinónimos:

• T-Butyloxycarbonylglycyl-L-Arginyl-L-Arginine 4-Methylcoumaryl-7-Amide
• Boc-Gly-Arg-Arg-Mca
• Boc-Gly-Arg-Arg-Amc
• tert-butyl N-[2-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]carbamate
• BOC-GRR-AMC
• L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]glycyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
• TERT-BUTYLOXYCARBONYL-GLYCYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE

Boc-Gly-Arg-Arg-AMC

CAS: 113866-14-1

A substrate for flavivirus proteases such as West Nile virus protease, yellow fever virus NS3 protease, and dengue virus NS2B-NS3 protease.Boc-GRR-AMC is cleaved by type II Metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana. Stock solutions of Boc-GRR-AMC are best prepared in DMSO.

Fórmula: C₂₉H₄₄N₁₀O₇

Pureza: 98.7%

Forma y color: White Powder

Peso molecular: 644.73

Ref: 01-4017086

Boc-Gly-Arg-Arg-AMC acetate salt

CAS: 113866-14-1

Boc-Gly-Arg-Arg-AMC acetate salt is a protease inhibitor that inhibits the activity of serine proteases. This protein is a potent and selective inhibitor of the NS3 protease from hepatitis C virus, which is responsible for the cleavage of polyproteins into mature proteins. Boc-Gly-Arg-Arg-AMC acetate salt has been shown to be effective in transfection experiments and polymerase chain reaction, as well as in inhibiting the activity of soybean trypsin and mammalian tissue proteases.

Fórmula: C₂₉H₄₄N₁₀O₇•(C₂H₄O₂)x

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 644.72 g/mol

Ref: 3D-FB110553

Boc-Gly-Arg-Arg-AMC

CAS: 113866-14-1

Boc-Gly-Arg-Arg-AMC is a research tool that has a high purity and is used in cell biology, antibody production, ion channels, and protein interactions. It is an inhibitor of ion channels, which can be used for pharmacology to study the function of ion channels. Boc-Gly-Arg-Arg-AMC has also been shown to inhibit binding between the ligand and receptor.

Fórmula: C₂₉H₄₄N₁₀O₇

Pureza: Min. 95%

Peso molecular: 644.72 g/mol

Ref: 3D-MGR-3142-V

Boc-Gly-Arg-Arg-AMC trifluoroacetate

CAS: 113866-14-1

Boc-Gly-Arg-Arg-AMC trifluoroacetate is a potent inhibitor of kinases, which are enzymes that play a crucial role in various cellular processes. It has been shown to effectively inhibit the activity of both Chinese and human kinases. This inhibitor has also demonstrated its efficacy as an anticancer agent by inducing apoptosis in cancer cells. Boc-Gly-Arg-Arg-AMC trifluoroacetate is a medicinal protein analog that can be used for the development of novel inhibitors with improved potency and selectivity. Its potential therapeutic applications make it a promising candidate for cancer treatment. Additionally, this compound can be detected in urine, making it an excellent biomarker for kinase activity in vivo.

Fórmula: C₂₉H₄₄N₁₀O₇•(C₂HF₃O₂)x

Pureza: Min. 95%

Forma y color: Powder

Ref: 3D-BB183183