CAS 1141-41-9

IDT307

CAS: 1141-41-9

IDT307, a fluorescent analog of MPP+, is a fluorescent substrate for DAT and can be used for rapid identification and characterization of PMAT inhibitors.

Fórmula: C₁₄H₁₇IN₂

Pureza: 97.58%

Forma y color: Solid

Peso molecular: 340.2

Ref: TM-T38516

IDT 307

CAS: 1141-41-9

IDT 307 is a novel compound that belongs to the class of inhibitors of transport. It has been shown to have an inhibitory effect on polymorphic IDO and its pro-inflammatory cytokines in mice deficient in this enzyme. IDT 307 also inhibits uptake of tryptophan into hematopoietic cells and reduces the levels of inflammatory cytokines, such as IL-1β, IL-6, and TNF-α. This drug has also been shown to have anti-depressant properties in mice with chronic bronchitis. IDT 307 is a molecule that tautomerizes between two forms: a crystalline polymorph and an amorphous form. The crystalline form is more stable than the amorphous form, but both forms are active against IDO activity.

Fórmula: C₁₄H₁₇IN₂

Pureza: Min. 95%

Peso molecular: 340.2 g/mol

Ref: 3D-BI180291