CAS 1142-20-7

Benzyloxi-carbonil-L-alanina

Descripción:

Benzyloxi-carbonil-L-alanina, comúnmente conocido como Z-L-alanina, es un derivado del aminoácido alanina donde el grupo amino está protegido por un grupo benzyloxycarbonilo (Z). Este compuesto se caracteriza por su apariencia cristalina blanca y es soluble en disolventes orgánicos como el metanol y el dimetilsulfóxido, pero tiene una solubilidad limitada en agua. El grupo Z sirve como un grupo protector en la síntesis de péptidos, permitiendo reacciones selectivas sin interferir con los grupos funcionales del aminoácido. El compuesto tiene una fórmula molecular que refleja su estructura, incorporando tanto la columna vertebral de alanina como la parte benzyloxycarbonilo. Su estabilidad bajo condiciones de laboratorio estándar lo convierte en un intermediario valioso en la síntesis orgánica y la química de péptidos. Además, la Z-L-alanina se utiliza a menudo en la preparación de varios péptidos y puede estar involucrada en el estudio de la estructura y función de las proteínas debido a su papel en la modificación de secuencias de aminoácidos. Los datos de seguridad indican que, al igual que muchas sustancias químicas, debe manejarse con cuidado, siguiendo los protocolos de seguridad apropiados.

Fórmula: C₁₁H₁₃NO₄

InChI: InChI=1S/C11H13NO4/c1-8(10(13)14)12-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,15)(H,13,14)/t8-/m0/s1

Clave InChI: InChIKey=TYRGLVWXHJRKMT-QMMMGPOBSA-N

SMILES: C(OC(N[C@H](C(O)=O)C)=O)C1=CC=CC=C1

Sinónimos:

• (2S)-2-[[(Benzyloxy)carbonyl]amino]propanoic acid
• (S)-2-(Benzyloxycarbonylamino)propanoic acid
• (S)-2-[(Benzyloxycarbonyl)amino]propionic acid
• <span class="text-smallcaps">L</span>-Alanine, N-[(phenylmethoxy)carbonyl]-
• <span class="text-smallcaps">L</span>-Alanine, N-carboxy-, N-benzyl ester
• <span class="text-smallcaps">L</span>-Carbobenzoxyalanine
• <span class="text-smallcaps">L</span>-Carbobenzyloxyalanine
• <span class="text-smallcaps">L</span>-Cbz alanine
• <span class="text-smallcaps">L</span>-N-(Benzyloxycarbonyl)alanine
• Alanine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Alanine, N-carboxy-, N-benzyl ester, L-
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-alanine
• Benzyloxycarbonyl-L-alanine
• Cbz-<span class="text-smallcaps">L</span>-Ala-OH
• L-Alanine, N-carboxy-, N-benzyl ester
• L-Carbobenzoxyalanine
• L-Carbobenzyloxyalanine
• L-N-(Benzyloxycarbonyl)alanine
• N-(Benzyloxycarbonyl)-(S)-alanine
• N-(Carbobenzoxy)-<span class="text-smallcaps">L</span>-alanine
• N-(Carbobenzoxy)-L-alanine
• N-Benzoxycarbonyl-<span class="text-smallcaps">L</span>-alanine
• N-Benzoxycarbonyl-L-alanine
• N-Benzyloxycarbonyl-L-alanin
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-alanine
• N-Carbobenzyloxy-L-alanine
• N-Cbz alanine
• N-[(Benzyloxy)carbonyl]-<span class="text-smallcaps">L</span>-alanine
• N-[(Benzyloxy)carbonyl]-L-alanine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-alanine
• N-[(Phenylmethoxy)carbonyl]-L-alanine
• N-benciloxicarbonil-L-alanina
• N-benzyloxycarbonyl-L-alanine
• Nsc 156978
• Nsc 88469
• z-Ala
• N-CBZ-L-Alanine
• (2S)-2-{[(benzyloxy)carbonyl]amino}propanoate
• Cbz-Ala-OH
• Z-L-Alanine
• Z-Ala-OH
• N-Cbz-L-Ala-OH
• N-[(benzyloxy)carbonyl]-D-alanine
• Cbz-L-alanine
• BenzyloxycarbonylLalanine

N-Carbobenzoxy-L-alanine

CAS: 1142-20-7

Fórmula: C₁₁H₁₃NO₄

Pureza: >99.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 223.23

Ref: 3B-C0633

N-Benzyloxycarbonyl-L-alanine, 98%

CAS: 1142-20-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₁H₁₃NO₄

Pureza: 98%

Forma y color: crystalline powder, White

Peso molecular: 223.23

Ref: 02-A16716

Z-Ala-OH

CAS: 1142-20-7

Bachem ID: 4000246.

Fórmula: C₁₁H₁₃NO₄

Pureza: 99.4%

Forma y color: White Powder

Peso molecular: 223.23

Ref: 01-4000246

Z-Ala-OH

CAS: 1142-20-7

Fórmula: C₁₁H₁₃NO₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 223.2252

Ref: IN-DA003SVU

Z-L-Alanine

CAS: 1142-20-7

Fórmula: C₁₁H₁₃NO₄

Peso molecular: 223.23

Ref: 7W-GM6987

Metaraminol Impurity 11

CAS: 1142-20-7

Fórmula: C₁₁H₁₃NO₄

Peso molecular: 223.23

Ref: 4Z-M-216014

L-Alanine, N-CBZ protected

CAS: 1142-20-7

L-Alanine, N-CBZ protected

Fórmula: C₁₁H₁₃NO₄

Pureza: 97%

Forma y color: white solid

Peso molecular: 223.22522g/mol

Ref: 54-OR61272

Z-Ala-OH

CAS: 1142-20-7

M03069 - Z-Ala-OH

Fórmula: C₁₁H₁₃NO₄

Pureza: 97%

Forma y color: Solid, White powder

Peso molecular: 223.228

Ref: 10-M03069

N-Benzyloxycarbonyl-L-alanine

Producto controlado

CAS: 1142-20-7

Applications N-Benzyloxycarbonyl-L-alanine is an intermediate in the synthesis of Perindopril (P287500), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
References Lees, K.R., et al.: Brit. J. Clin. Pharmacol., 23, 159 (1987); Morgan, T., et al.: J. Cardiovasc. Pharmacol., 10, Supp. 7, S116, (1987)

Fórmula: C₁₁H₁₃NO₄

Forma y color: Neat

Peso molecular: 223.23

Ref: TR-B286615

Z-L-Alanine extrapure, 99%

CAS: 1142-20-7

Fórmula: C₁₁H₁₃NO₄

Pureza: min. 99%

Forma y color: White, Crystalline powder, Clear, Colourless

Peso molecular: 223.21

Ref: SR-46096

Metaraminol Impurity 11

CAS: 1142-20-7

Fórmula: C₁₁H₁₃NO₄

Peso molecular: 223.23

Ref: ST-EA-CP-M97017

Z-L-Alanine

CAS: 1142-20-7

Z-L-Alanine is a cytosolic enzyme inhibitor that inhibits the activity of enzymes involved in protein catalysis. This inhibition is stereoselective, with the L-enantiomer having the stronger inhibitory effect. Z-L-Alanine has been shown to be an effective inhibitor of proteolytic enzymes and has been used as an additive in buffers to prevent enzymatic degradation. Molecular modeling studies have demonstrated that Z-L-Alanine can bind to the active site of these enzymes and inhibit their activity by binding to the catalytic triad of serine, aspartate, and histidine residues. The molecular structure of Z-L-Alanine resembles that of a natural substrate for these enzymes, which may account for its effectiveness in inhibiting them. FTIR spectroscopy has confirmed the presence of Z-L-alanine in a sample obtained from a bacterial culture. Liquid chromatography has shown that this amino acid is present at high levels in various

Fórmula: C₁₁H₁₃NO₄

Pureza: Min. 95%

Forma y color: White Off-White Powder

Peso molecular: 223.23 g/mol

Ref: 3D-FA28886