CAS 1142096-20-5

4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile-d8

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CAS: 1142096-20-5

Applications 4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile-d8 is an intermediate from the synthesis of Etravirine-d8 (E937003). Etravirine-d8 is a novel labelled HIV reverse transcriptase inhibitor useful in treatment of HIV infection.
References Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008); Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008)

Fórmula: C₂₀D₈H₆ClN₅O

Forma y color: Neat

Peso molecular: 383.86

Ref: TR-C380824