CAS 1145-80-8

N-(Benzyloxi-carbonil)-L-serina

Descripción:

N-(Benzyloxi-carbonil)-L-serina, también conocido como Z-L-serina, es un derivado del aminoácido L-serina, caracterizado por la presencia de un grupo protector benzyloxycarbonilo (Z) en el grupo amino. Este compuesto es típicamente un sólido cristalino blanco a blanco amarillento y es soluble en disolventes orgánicos polares como el metanol y el dimetilsulfóxido, pero menos soluble en disolventes no polares. Se utiliza comúnmente en la síntesis de péptidos como un grupo protector para el grupo amino, permitiendo reacciones selectivas en el grupo carboxilo o en las cadenas laterales. El grupo Z se puede eliminar en condiciones ácidas suaves, facilitando la desprotección del grupo amino cuando es necesario. N-(Benzyloxi-carbonil)-L-serina también es de interés en la investigación bioquímica y en aplicaciones farmacéuticas debido a su papel en la síntesis de péptidos y proteínas. Su estructura molecular incluye un centro quiral, lo que lo hace ópticamente activo, y exhibe propiedades típicas de los aminoácidos, como la capacidad de participar en enlaces de hidrógeno y formar especies zwitteriónicas en solución.

Fórmula: C₁₁H₁₃NO₅

InChI: InChI=1S/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m0/s1

Clave InChI: InChIKey=GNIDSOFZAKMQAO-VIFPVBQESA-N

SMILES: C(OC(N[C@H](C(O)=O)CO)=O)C1=CC=CC=C1

Sinónimos:

• (2S)-2-[(Benzyloxycarbonyl)amino]-3-hydroxypropanoic acid
• (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-hydroxypropanoic acid
• (2S)-3-Hydroxy-2-(phenylmethoxycarbonylamino)propanoic acid
• (S)-2-(Benzyloxycarbonylamino)-3-hydroxypropanoic acid
• <span class="text-smallcaps">L</span>-Carbobenzyloxy serine
• <span class="text-smallcaps">L</span>-Serine, N-[(phenylmethoxy)carbonyl]-
• <span class="text-smallcaps">L</span>-Serine, N-carboxy-, N-benzyl ester
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-serine
• Cbz-L-serine
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-serine
• N-Benzyloxycarbonyl-L-serine
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-serine
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-serine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-serine
• N-[(Phenylmethoxy)carbonyl]serine
• N-[(benzyloxy)carbonyl]-L-serine
• N-[(benzyloxy)carbonyl]serine
• N-cbz-l-serine
• NSC 286604
• Serine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Z-Ser-OH
• L-Serine, N-[(phenylmethoxy)carbonyl]-
• L-Serine, N-carboxy-, N-benzyl ester
• N-[(Phenylmethoxy)carbonyl]-L-serine

N-Benzyloxycarbonyl-L-serine

CAS: 1145-80-8

Fórmula: C₁₁H₁₃NO₅

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 239.23

Ref: 3B-C0635

N-Benzyloxycarbonyl-L-serine, 99%

CAS: 1145-80-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₁H₁₃NO₅

Pureza: 99%

Forma y color: Powder, White

Peso molecular: 239.23

Ref: 02-A19050

Z-Ser-OH

CAS: 1145-80-8

Educt in Hoveyda’s synthesis of L-3-fluoroalanine and N-methyl-L-3-fluoroalanine derivatives via the oxazolidinone.

Fórmula: C₁₁H₁₃NO₅

Pureza: > 99%

Forma y color: White

Peso molecular: 239.23

Ref: 01-4001465

L-Serine, N-[(phenylmethoxy)carbonyl]-

CAS: 1145-80-8

Fórmula: C₁₁H₁₃NO₅

Pureza: 97%

Forma y color: Solid

Peso molecular: 239.2246

Ref: IN-DA000EKT

Z-Ser-OH

CAS: 1145-80-8

Fórmula: C₁₁H₁₃NO₅

Peso molecular: 239.23

Ref: 7W-GM2492

Carbobenzyloxy-l-serine

CAS: 1145-80-8

Carbobenzyloxy-l-serine

Pureza: 98%

Peso molecular: 239.22g/mol

Ref: 54-OR322046

Z-L-Serine extrapure, 99%

CAS: 1145-80-8

Fórmula: C₁₁H₁₃NO₅

Pureza: min. 99%

Forma y color: White to Cream powder, Crystalline powder

Peso molecular: 239.2

Ref: SR-75675

Z-Ser-OH

CAS: 1145-80-8

M03053 - Z-Ser-OH

Fórmula: C₁₁H₁₃NO₅

Pureza: 97%

Forma y color: Solid

Peso molecular: 239.227

Ref: 10-M03053

N-Carboxybenzyl-L-serine-13C3

Producto controlado

CAS: 1145-80-8

Applications is an intermediate used in the synthesis of L-3-Phosphoglyceric Acid 13C3 (P358007), which is carbon-13 labelled L-3-Phosphoglyceric Acid. 3-Phosphoglyceric acid is involved in glutamate biosynthesis in syntrophus aciditrophicus. 3-Phosphoglyceric acid can also be used to study pyruvate carboxylation in SDH-deficient kidney mouse cells.
References Kim, M., et al.: Appl. Environ. Microbiol. 81, 8434 (2015); Cardaci, S., et al.: Nat. Cell. Biol. 17, 1317 (2015)

Fórmula: C₃C₈H₁₃NO₅

Forma y color: Neat

Peso molecular: 242.20258

Ref: TR-C182416

N-Carboxybenzyl-L-serine

Producto controlado

CAS: 1145-80-8

Applications Building block in peptide synthesis.
References Pansare, S. V.; Org. Synth. 70, 10(1992)

Fórmula: C₁₁H₁₃NO₅

Forma y color: Neat

Peso molecular: 239.22

Ref: TR-C182415

N-Cbz-L-serine

CAS: 1145-80-8

N-Cbz-L-serine is a synthetic amino acid that has been shown to have antimicrobial effects. It has been found to inhibit the growth of bacteria, fungi, and protozoa by inhibiting their cell membranes. This amino acid also inhibits the synthesis of phospholipids in bacterial cell walls and may be used as an antimicrobial agent for industrial applications. N-Cbz-L-serine contains both a hydroxy group and a hydroxyl group, which are essential for its antibacterial activity. The fatty acids present in this compound can be either saturated or unsaturated. Multigram quantities of N-Cbz-L-serine have been produced with high purity using asymmetric synthesis methods.

Fórmula: C₁₁H₁₃NO₅

Pureza: Min. 95%

Forma y color: White/Off-White Solid

Peso molecular: 239.22 g/mol

Ref: 3D-FC19786