CAS 114745-26-5

5'-O-DMT-N2-Isobutiril-2'-O-metil-D-guanosina

Descripción:

5'-O-DMT-N2-Isobutiril-2'-O-metil-D-guanosina es un nucleósido modificado que presenta varias características químicas distintivas. Es un derivado de guanosina, que es uno de los cuatro nucleósidos principales que componen el ARN. La presencia de un grupo 5'-dimetoxitriptil (DMT) indica que este compuesto probablemente se utiliza en la síntesis de oligonucleótidos, ya que el grupo DMT actúa como un grupo protector para el hidroxilo 5'. La modificación N2-isobutirilo introduce un grupo acilo en la posición del nitrógeno, lo que puede influir en la reactividad y estabilidad del nucleósido. Además, la modificación 2'-O-metilo mejora la resistencia del compuesto a la degradación enzimática, haciéndolo más adecuado para aplicaciones terapéuticas. En general, este compuesto se caracteriza por su complejidad estructural, que permite interacciones específicas en procesos bioquímicos, y su utilidad potencial en la investigación y el desarrollo farmacéutico, particularmente en el contexto de tecnologías basadas en ARN.

Sinónimos:

• DMT-2'-OMe-ibu-G
• 5'-O-DMT-N2-Isobutyryl-2'-O-Methyl-Guanosine

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine, 98%

CAS: 114745-26-5

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Fórmula: C₃₆H₃₉N₅O₈

Pureza: 98%

Peso molecular: 669.72

Ref: 02-J65583

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-

CAS: 114745-26-5

Fórmula: C₃₆H₃₉N₅O₈

Pureza: 98%

Forma y color: Solid

Peso molecular: 669.7236

Ref: IN-DA000F4X

5''-O-DMT-N2-isobutyryl-2''-O-methylguanosine

CAS: 114745-26-5

Fórmula: C₃₆H₃₉N₅O₈

Pureza: ≥ 98.0%

Forma y color: White to off-white powder

Peso molecular: 669.72

Ref: 7W-GN3279

5’-​O-​[Bis(4-​Methoxyphenyl)​Phenylmethyl]​-​2’-​O-​Methyl-​N-​(2-​Methyl-​1-​Oxopropyl)​Guanosine

CAS: 114745-26-5

5’-​O-​[Bis(4-​Methoxyphenyl)​Phenylmethyl]​-​2’-​O-​Methyl-​N-​(2-​Methyl-​1-​Oxopropyl)​Guanosine

Pureza: 99%

Peso molecular: 669.72g/mol

Ref: 54-OR1028848

5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine

CAS: 114745-26-5

5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine is a nucleoside that has been synthesized using an oxime opening of the 5' position and a methylation at the 2' position. It has been shown to have an affinity for tissues in a chemotactic assay. The compound is minimised to remove non-specific binding sites, avoiding false positives on the checklist. This molecule has been analysed with fluorescence spectroscopy and microscopy techniques, which revealed that it is distributed in tissues as well as being found in dragonflies. It was also shown to be transduced by muscle cells and geochemically detected in limestone from China.

Fórmula: C₃₆H₃₉N₅O₈

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 669.74 g/mol

Ref: 3D-ND03004

5′-​O-​[Bis(4-​methoxyphenyl)phenylmethyl]​-2′-​O-methyl-​N-(2-​methyl-​1-​oxopropyl)guanosine

CAS: 114745-26-5

Pureza: 98%

Peso molecular: 669.735

Ref: 10-F988000

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine

CAS: 114745-26-5

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside synthesized through oxime ring-opening at the 5' position and methylation at the 2' position. In chemotaxis assays, 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine demonstrates tissue affinity.

Fórmula: C₃₆H₃₉N₅O₈

Forma y color: Solid

Peso molecular: 669.724

Ref: TM-T206273