CAS 1148-11-4

Benzyloxi-carbonil-L-prolina

Descripción:

Benzyloxi-carbonil-L-prolina, comúnmente conocido como Z-Prolina, es un derivado del aminoácido prolina, caracterizado por la presencia de un grupo protector benzyloxycarbonilo (Z). Este compuesto se utiliza típicamente en la síntesis de péptidos como un grupo protector para la funcionalidad amino de la prolina, lo que ayuda a prevenir reacciones no deseadas durante el proceso de síntesis. La Z-Prolina es un sólido cristalino blanco a blanco sucio que es soluble en disolventes orgánicos como el metanol y el dimetilsulfóxido, pero tiene una solubilidad limitada en agua. Su estructura molecular incluye un esqueleto de prolina, que contribuye a sus propiedades conformacionales únicas, haciéndola valiosa en el diseño de péptidos y proteínas. El compuesto es estable bajo condiciones normales de laboratorio, pero puede sufrir hidrólisis o desprotección bajo condiciones ácidas o básicas. Debido a su papel en la química de péptidos, la Z-Prolina es significativa en la investigación farmacéutica y el desarrollo de compuestos biológicamente activos. Se deben consultar los datos de seguridad para su manipulación, como con cualquier sustancia química.

Fórmula: C₁₃H₁₅NO₄

InChI: InChI=1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m0/s1

Clave InChI: InChIKey=JXGVXCZADZNAMJ-NSHDSACASA-N

SMILES: C(OCC1=CC=CC=C1)(=O)N2[C@H](C(O)=O)CCC2

Sinónimos:

• (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(phenylmethyl) ester
• (2S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
• (2S)-1-Phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
• (2S)-1-[(benzyloxy)carbonyl]pyrrolidine-2-carboxylate
• (S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
• 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (S)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, <span class="text-smallcaps">L</span>-
• 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, L-
• 1-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• 1-(Benzyloxycarbonyl)-L-proline
• 1-Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• 1-Carbobenzoxy-L-proline
• 1-[(Benzyloxy)Carbonyl]Proline
• 1-[(benzyloxy)carbonyl]-D-proline
• 1-[(benzyloxy)carbonyl]-L-proline
• <span class="text-smallcaps">L</span>-Cbz-Proline
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-proline
• Benzyloxycarbonyl-L-proline
• Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• Carbobenzoxy-L-proline
• Carbobenzoxy-S-proline
• Carbobenzyloxy-<span class="text-smallcaps">L</span>-proline
• Carbobenzyloxy-L-proline
• Cbz-<span class="text-smallcaps">L</span>-Pro-OH
• Cbz-L-Pro-OH
• Cbz-L-proline
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• N-(Carbobenzyloxy)-<span class="text-smallcaps">L</span>-proline
• N-Benzyloxycarbonyl-(S)-proline
• N-Benzyloxycarbonyl-L-prolin
• N-Benzyloxycarbonyl-L-proline
• N-CBZ-L-Proline N-Carbobenzyloxy-L-proline
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• N-Carbobenzoxy-L-proline
• N-Carbobenzyloxy-(S)-proline
• N-Cbz-<span class="text-smallcaps">L</span>-proline
• N-Cbz-L-Pro-OH
• N-Cbz-L-proline
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-proline
• N-[(Phenylmethoxy)carbonyl]-L-proline
• N-benciloxicarbonil-L-prolina
• N-cbz-L-proline crystalline
• Z-L-Proline
• Z-Pro-OH
• N-CARBOBENZYLOXY-L-PROLINE
• N-ALPHA-BENZYLOXYCARBONYL-L-PROLINE
• N-ALPHA-CBZ-L-PROLINE
• (2S)-1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID
• CBZ-PRO-OH
• N-ALPHA-CARBOBENZOXY-L-PROLINE
• (S)-N-CBZ-PYRROLIDINE-2-CARBOXYLIC ACID
• N-CBZ-L-PROLINE-OH
• Z-L-PRO-OH
• N-ALPHA-CARBOBENZOXY-L-PYRROLIDINE-2-CARBOXYLIC ACID
• L-CBZ-PROLINE

N-Benzyloxycarbonyl-L-proline

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 249.27

Ref: 3B-C0713

N-Benzyloxycarbonyl-L-proline, 98+%

CAS: 1148-11-4

N-(Benzyloxycarbonyl)-L-proline is a potent inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. It is also used in the synthesis of N-(L-Prolyl)--alanine which is a derivative of the naturally occurring beta amino acid -Alanine. T

Fórmula: C₁₃H₁₄NO₄

Pureza: 98+%

Forma y color: Powder or crystalline powder or crystals or granules, White to cream

Peso molecular: 248.26

Ref: 02-B21672

Z-Pro-OH

CAS: 1148-11-4

Bachem ID: 4001343.

Fórmula: C₁₃H₁₅NO₄

Pureza: 99.1%

Forma y color: White

Peso molecular: 249.27

Ref: 01-4001343

Z-Pro-OH

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 249.2625

Ref: IN-DA007RF9

(2S)-Pyrrolidine-2-carboxylic acid, N-CBZ protected

CAS: 1148-11-4

(2S)-Pyrrolidine-2-carboxylic acid, N-CBZ protected

Fórmula: C₁₃H₁₅NO₄

Pureza: 98%

Forma y color: white solid

Peso molecular: 249.26g/mol

Ref: 54-OR61280

Carbobenzoxyproline

CAS: 1148-11-4

Carbobenzoxyproline

Pureza: ≥98%

Peso molecular: 249.26g/mol

Ref: 54-BUP19312

Z-Pro-OH

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Peso molecular: 249.27

Ref: 7W-GM1976

Carbobenzoxyproline

CAS: 1148-11-4

Carbobenzoxyproline (Carbobenzoxy-S-proline) is a prolidase inhibitor.

Fórmula: C₁₃H₁₅NO₄

Pureza: 99.79%

Forma y color: White To Light Yellow Crystal Powder

Peso molecular: 249.26

Ref: TM-T20125

Z-Pro-OH

CAS: 1148-11-4

M03066 - Z-Pro-OH

Fórmula: C₁₃H₁₅NO₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 249.266

Ref: 10-M03066

N-Benzyloxycarbonyl-L-proline

CAS: 1148-11-4

N-Benzyloxycarbonyl-L-proline is a cationic polymerization inhibitor that has been shown to inhibit the growth of Pseudomonas aeruginosa. It inhibits bacterial growth by inhibiting the production of collagen, an important component in the cell wall. N-Benzyloxycarbonyl-L-proline is also used as a histological staining agent and has been shown to be effective against breast cancer cells resistant to tamoxifen therapy.

Fórmula: C₁₃H₁₅NO₄

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 249.26 g/mol

Ref: 3D-FB37965

Z-L-Proline extrapure, 99%

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Pureza: min. 99%

Forma y color: White, Crystalline powder

Peso molecular: 249.3

Ref: SR-31688

N-(Benzyloxycarbonyl)-L-proline

Producto controlado

CAS: 1148-11-4

Applications N-(Benzyloxycarbonyl)-L-proline is a potent in vitro and in vivo inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. N-(Benzyloxycarbonyl)-L-proline is also used in the synthesis of N-(L-Prolyl)-β-alanine (P756190) which is a derivative of the naturally occurring beta amino acid β-Alanine (A637320).
References Lupi, A., et al.: BBA-Mol. Cell Res., 1744, 157 (2005)

Fórmula: C₁₃H₁₅NO₄

Forma y color: Neat

Peso molecular: 249.26

Ref: TR-B287810

Acalabrutinib Impurity 18

CAS: 1148-11-4

Fórmula: C₁₃H₁₅NO₄

Peso molecular: 249.27

Ref: ST-EA-CP-A165007