CAS 116560-97-5

ácido 4-[[(1S)-1-[[(2S)-2-[[(2S)-2-[(1-carboxi-3-fenil-propil)amino]propanol]amino]propanol]carbamoil]-2-fenil-etil]amino]benzoico

Descripción:

La sustancia química conocida como ácido 4-[[(1S)-1-[[(2S)-2-[[(2S)-2-[(1-carboxi-3-fenil-propil)amino]propanol]amino]propanol]carbamoil]-2-fenil-etil]amino]benzoico, con el número CAS 116560-97-5, es un compuesto orgánico complejo caracterizado por su estructura multifuncional, que incluye múltiples residuos de aminoácidos y un grupo ácido carboxílico. Este compuesto probablemente exhiba propiedades típicas de péptidos o moléculas similares a péptidos, como solubilidad en disolventes polares y potencial actividad biológica, posiblemente como agente farmacéutico o sonda bioquímica. Su estructura sugiere la presencia de centros quirales, que pueden impartir propiedades estereocómicas específicas que influyen en su interacción con objetivos biológicos. La presencia de grupos fenilo indica potencial para interacciones aromáticas, mientras que el moiety ácido carboxílico puede contribuir a su acidez y capacidad para formar sales. En general, la intrincada estructura de este compuesto sugiere un papel en sistemas biológicos complejos, potencialmente involucrando interacciones enzimáticas o unión a receptores.

Fórmula: C₃₂H₃₆N₄O₇

InChI: InChI=1/C32H36N4O7/c1-20(33-26(32(42)43)18-13-22-9-5-3-6-10-22)28(37)34-21(2)29(38)36-30(39)27(19-23-11-7-4-8-12-23)35-25-16-14-24(15-17-25)31(40)41/h3-12,14-17,20-21,26-27,33,35H,13,18-19H2,1-2H3,(H,34,37)(H,40,41)(H,42,43)(H,36,38,39)/t20-,21-,26?,27-/m0/s1

SMILES: C[C@@H](C(=N[C@@H](C)C(=NC(=O)[C@H](Cc1ccccc1)Nc1ccc(cc1)C(=O)O)O)O)NC(CCc1ccccc1)C(=O)O

Sinónimos:

• N-(1-carboxy-3-phenylpropyl)-alanyl-alanyl-phenylalanine-4-aminobenzoate
• N-(1-carboxy-3-phenylpropyl)-L-alanyl-N-{(2S)-2-[(4-carboxyphenyl)amino]-3-phenylpropanoyl}-L-alaninamide

N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH

CAS: 116560-97-5

Specific inhibitor of thimet oligopeptidase (soluble metalloendopeptidase, EC 3.4.24.15) (Ki = 0.027 ± 0.003 µM). Neprilysin (Endopeptidase-2, EC 3.4.24.11) converts Cpp-AAF-pAb into a potent inhibitor of angiotensin-converting enzyme (ACE).

Fórmula: C₃₂H₃₆N₄O₇

Pureza: 98.2%

Forma y color: White Powder

Peso molecular: 588.66

Ref: 01-4050213

Cpp-AAF-pAb

CAS: 116560-97-5

Cpp-AAF-pAb is a synthetic peptide that corresponds to the amino acid sequence of the C terminus of human basic fibroblast growth factor (bFGF) and has been shown to have a variety of effects on cells. It has been used in cell culture studies to measure the effect of bFGF on renal blood flow, which is an important marker for kidney disease. In addition, this peptide inhibits tumor cell growth and has antinociceptive properties in rats. The inhibition of tumor cell growth may be due to its ability to inhibit metalloendopeptidases and polyclonal antibodies.

Fórmula: C₃₂H₃₆N₄O₇

Pureza: Min. 95%

Peso molecular: 588.67 g/mol

Ref: 3D-IAP-3754-PI

N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt

CAS: 116560-97-5

The N-[(RS)-1-carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt is a synthetic substrate for the study of metalloendopeptidase. This compound was used to develop a model system to study the function of human liver, and has been shown to inhibit the growth of PC12 cells. The N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt is also an experimental model for congestive heart failure. This compound has been shown to increase glomerular filtration rate in experimental animals as well as basic fibroblast growth factor activity in cell culture by increasing intracellular calcium levels.

Fórmula: C₃₂H₃₆N₄O₇

Pureza: Min. 95%

Peso molecular: 588.65 g/mol

Ref: 3D-FR111118