CAS 117976-89-3

Rabeprazol

Descripción:

Rabeprazol es un inhibidor de la bomba de protones (IBP) comúnmente utilizado para tratar condiciones como la enfermedad por reflujo gastroesofágico (ERGE) y las úlceras pépticas al reducir la producción de ácido estomacal. Se caracteriza por su fórmula química, que incluye un grupo sulfinilo, y su estructura presenta un anillo de piridina, lo que contribuye a su actividad farmacológica. Rabeprazol se administra típicamente en su forma de sal sódica y es conocido por su rápido inicio de acción y su duración relativamente larga de efecto. La sustancia se absorbe generalmente bien en el tracto gastrointestinal, siendo su biodisponibilidad influenciada por la ingesta de alimentos. Rabeprazol se metaboliza principalmente en el hígado a través de las enzimas del citocromo P450, lo que da lugar a varios metabolitos, algunos de los cuales son farmacológicamente activos. Sus efectos terapéuticos a menudo se acompañan de un perfil de seguridad favorable, aunque los efectos secundarios potenciales pueden incluir dolor de cabeza, trastornos gastrointestinales y, en casos raros, condiciones más graves. En general, Rabeprazol es un medicamento eficaz para el manejo de trastornos relacionados con el ácido, contribuyendo a mejorar los resultados en la salud gastrointestinal de los pacientes.

Fórmula: C₁₈H₂₁N₃O₃S

InChI: InChI=1/C11H16ClNO2/c1-9-10(8-12)13-5-4-11(9)15-7-3-6-14-2/h4-5H,3,6-8H2,1-2H3

Clave InChI: InChIKey=YREYEVIYCVEVJK-UHFFFAOYSA-N

SMILES: S(CC1=C(C)C(OCCCOC)=CC=N1)(=O)C=2NC=3C(N2)=CC=CC3

Sinónimos:

• 117976-89-3
• 1H-Benzimidazole, 2-[[[4-(3-Methoxypropoxy)-3-Methyl-2-Pyridinyl]Methyl]Sulfinyl]-
• 2-(Chloromethyl)-4-(3-Methoxypropoxy)-3-Methylpyridine
• 2-({[4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole
• 2-[4-(3-Methoxy-propoxy)-3-methyl-pyridin-2-ylmethanesulfinyl]-1H-benzoimidazole
• 2-[[[3-Methyl-4-(3-methoxypropoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[3-Methyl-4-(3-methoxypropoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridyl]methyl]sulfinyl]benzimidazole
• Dexrabeprazol
• Habeprazole
• Ly 307640
• Newprazole
• Pariets
• Pariprazole
• Rabeloc
• Rabemax
• Rabiral
• Rabeprazole
• Rabeprazole Sodium (200 mg) (Sodium 2-[(R)-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]benzimidazol-1-ide hydrate)
• 2-[[4-(3-methoxypropoxy)-3-methyl-pyridin-2-yl]methylsulfinyl]-1h-benzoimidazole
• 1H-1,3-benzimidazol-2-yl [4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl sulfoxide-sodium salt
• 2-[(S)-{[4-(3-Methoxypropoxy)-3-Methylpyridin-2-yl]Methane}sulfinyl]-1H-1,3-benzodiazole
• y-307640
• 2-[3-Methyl-4-(3-methoxypropoxy)-2-pyridinylmethylsulfinyl]-1H-benzimidazole
• 2-(CHOLROMETHYL)-4-(3-METHOXYPROPOXY)-3-METHYLPYRIDINE
• Rebeprazole
• 2-(((4-(3-Methoxypropoxy)-3-Methylpyridin-2-yl)Methyl)sulfinyl)-1H-benzo[d]iMidazole

Rabeprazole Sodium Salt

CAS: 117976-89-3, 117976-90-6

Fórmula: C₁₈H₂₀N₃NaO₃S

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 381.43

Ref: 3B-R0115

Rabeprazole

CAS: 117976-89-3

Fórmula: C₁₈H₂₁N₃O₃S

Peso molecular: 359.44

Ref: ST-EA-CP-R5041

1H-​Benzimidazole, 2-​[[[4-​(3-​methoxypropoxy)​-​3-​methyl-​2-​pyridinyl]​methyl]​sulfinyl]​-

CAS: 117976-89-3

Fórmula: C₁₈H₂₁N₃O₃S

Pureza: 98%

Forma y color: Solid

Peso molecular: 359.4426

Ref: IN-DA0081D1

Rabeprazole

CAS: 117976-89-3

Rabeprazole

Pureza: ≥95%

Peso molecular: 359.44g/mol

Ref: 54-BUP06414

Rabeprazole

CAS: 117976-89-3

Fórmula: C₁₈H₂₁N₃O₃S

Peso molecular: 359.44

Ref: 7W-GP0914

Rabeprazole

CAS: 117976-89-3

Fórmula: C₁₈H₂₁N₃O₃S

Forma y color: Off-White Solid

Peso molecular: 359.44

Ref: 4Z-R-201

Rabeprazole-d4

CAS: 117976-89-3

Fórmula: C₁₈H₁₇N₃O₃SD₄

Peso molecular: 363.47

Ref: 4Z-R-202

Rabeprazole

CAS: 117976-89-3

Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells and can be used in the study of gastric ulcers.

Fórmula: C₁₈H₂₁N₃O₃S

Pureza: 97.06%

Forma y color: White To Yellowish Crystalline Powder

Peso molecular: 359.44

Ref: TM-T19826

Rabeprazole

CAS: 117976-89-3

Rabeprazole is a proton pump inhibitor that suppresses the production of stomach acid by blocking the H+/K+ ATPase enzyme. It is used for the treatment of gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. Rabeprazole has been shown to be more effective than omeprazole in reducing gastric acid secretion in two-way crossover studies. Rabeprazole also has been shown to inhibit the growth of antibiotic-resistant strains of bacteria. In addition, rabeprazole binds to metal ions like iron and copper, which may affect its pharmacokinetics and efficacy. This drug is currently being investigated as an analytical method for determination of proton pump inhibitors in human serum and urine samples by electrochemical impedance spectroscopy (EIS).

Fórmula: C₁₈H₂₁N₃O₃S

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 359.44 g/mol

Ref: 3D-IM57864

Rabeprazole

Producto controlado

CAS: 117976-89-3

Stability Hygroscopic
Applications Rabeprazole is a partially reversible gastric proton pump inhibitor.
References Morii, M., and Takeguchi, N.: J. Biol. Chem., 268, 21553 (1993); Yasuda, S., et al.: Int. J. Clin. Pharmacol. Ther., 32, 466 (1994); Cloud, M.L., et al.: Dig. Dis. Sci., 43, 993 (1998)

Fórmula: C₁₈H₂₁N₃O₃S

Forma y color: Neat

Peso molecular: 359.44

Ref: TR-R070540